Literature DB >> 21491938

Ligand-promoted C-3 selective C-H olefination of pyridines with Pd catalysts.

Mengchun Ye1, Guo-Lin Gao, Jin-Quan Yu.   

Abstract

Pd-catalyzed C-3 selective olefination of pyridines is developed for the first time using 1,10-phenanthroline as the ligand. This finding provides a novel disconnection for the synthesis of pyridine-containing alkaloids and drug molecules as well as a new approach for developing Pd-catalyzed C-H functionalizations of pyridines.
© 2011 American Chemical Society

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Year:  2011        PMID： 21491938     DOI： 10.1021/ja2021075

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  22 in total

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Journal:  J Am Chem Soc       Date:  2013-07-09       Impact factor: 15.419

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Journal:  J Am Chem Soc       Date:  2016-04-05       Impact factor: 15.419

8.  Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability.

Authors:  Fionn O'Hara; Donna G Blackmond; Phil S Baran
Journal:  J Am Chem Soc       Date:  2013-07-30       Impact factor: 15.419

9.  Recent Advances in the C-H-Functionalization of the Distal Positions in Pyridines and Quinolines.

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10.  A Robust Protocol for Pd(II)-catalyzed C-3 Arylation of (1H) Indazoles and Pyrazoles: Total Synthesis of Nigellidine Hydrobromide.

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