Literature DB >> 21487029

Heterogeneous cardiac proteasomes: mandated by diverse substrates?

Sarah B Scruggs1, Peipei Ping, Chenggong Zong.   

Abstract

Proteasome biology has taken central stage in cardiac physiology and pathophysiology. The molecular heterogeneity of proteasome subpopulations supports the specificity of proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of proteasome function should inspire new therapeutic strategies for combating cardiac disease.

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Year:  2011        PMID： 21487029     DOI： 10.1152/physiol.00039.2010

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  9 in total

Review 1.  Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics.

Authors:  Sarah B Scruggs; Nobel C Zong; Ding Wang; Enrico Stefani; Peipei Ping
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-04-20       Impact factor: 4.733

Review 2.  Proteasome functional insufficiency in cardiac pathogenesis.

Authors:  Xuejun Wang; Jie Li; Hanqiao Zheng; Huabo Su; Saul R Powell
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-09-23       Impact factor: 4.733

3.  A retrospective analysis of 3954 patients in phase 2/3 trials of bortezomib for the treatment of multiple myeloma: towards providing a benchmark for the cardiac safety profile of proteasome inhibition in multiple myeloma.

Authors:  Jacob P Laubach; Javid J Moslehi; Sanjeev A Francis; Jesús F San Miguel; Pieter Sonneveld; Robert Z Orlowski; Philippe Moreau; Laura Rosiñol; Edward A Faber; Peter Voorhees; Maria-Victoria Mateos; Loreta Marquez; Huaibao Feng; Avinash Desai; Helgi van de Velde; Jennifer Elliott; Hongliang Shi; Edward Dow; Nishith Jobanputra; Dixie-Lee Esseltine; Liviu Niculescu; Kenneth C Anderson; Sagar Lonial; Paul G Richardson
Journal:  Br J Haematol       Date:  2017-05-03       Impact factor: 6.998

4.  Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice.

Authors:  Jie Li; Kathleen M Horak; Huabo Su; Atsushi Sanbe; Jeffrey Robbins; Xuejun Wang
Journal:  J Clin Invest       Date:  2011-08-15       Impact factor: 14.808

Review 5.  p62 Stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress.

Authors:  Huabo Su; Xuejun Wang
Journal:  Trends Cardiovasc Med       Date:  2011-11       Impact factor: 6.677

6.  Clarifying the cardiac proteasome paradox: protein quality control.

Authors:  Christopher C Glembotski
Journal:  Circ Res       Date:  2012-08-17       Impact factor: 17.367

Review 7.  Ubiquitin and Ubiquitin-like proteins in cardiac disease and protection.

Authors:  Jie Li; John A Johnson; Huabo Su
Journal:  Curr Drug Targets       Date:  2018       Impact factor: 3.465

8.  Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human.

Authors:  Ding Wang; Caiyun Fang; Nobel C Zong; David A Liem; Martin Cadeiras; Sarah B Scruggs; Hongxiu Yu; Allen K Kim; Pengyuan Yang; Mario Deng; Haojie Lu; Peipei Ping
Journal:  Mol Cell Proteomics       Date:  2013-09-15       Impact factor: 5.911

Review 9.  Protein Quality Control at the Sarcomere: Titin Protection and Turnover and Implications for Disease Development.

Authors:  Sebastian Kötter; Martina Krüger
Journal:  Front Physiol       Date:  2022-06-30       Impact factor: 4.755
  9 in total

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