Literature DB >> 21486171

Open-label uridine for treatment of depressed adolescents with bipolar disorder.

Douglas G Kondo1, Young-Hoon Sung, Tracy L Hellem, Kristen K Delmastro, Eun-Kee Jeong, Namkug Kim, Xianfeng Shi, Perry F Renshaw.   

Abstract

This report is an open-label case series of seven depressed adolescents with bipolar disorder treated with uridine for 6 weeks. Treatment response was measured with the Children's Depression Rating Scale-Revised and the Clinical Global Impressions scale. Uridine was associated with decreased depressive symptoms, and was well tolerated by study participants. Further systematic studies of uridine are warranted.

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Year:  2011        PMID： 21486171      PMCID： PMC3080753          DOI： 10.1089/cap.2010.0054

Source DB:  PubMed          Journal:  J Child Adolesc Psychopharmacol        ISSN： 1044-5463            Impact factor:   2.576


  33 in total

1.  A pharmacotherapy algorithm for stabilization and maintenance of pediatric bipolar disorder.

Authors:  Mani N Pavuluri; David B Henry; Bhargavi Devineni; Julie A Carbray; Michael W Naylor; Philip G Janicak
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2004-07       Impact factor: 8.829

2.  Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder.

Authors:  Ana C Andreazza; Li Shao; Jun-Feng Wang; L Trevor Young
Journal:  Arch Gen Psychiatry       Date:  2010-04

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Authors:  D M Becroft; L I Phillips; A Simmonds
Journal:  J Pediatr       Date:  1969-11       Impact factor: 4.406

4.  A rating scale for mania: reliability, validity and sensitivity.

Authors:  R C Young; J T Biggs; V E Ziegler; D A Meyer
Journal:  Br J Psychiatry       Date:  1978-11       Impact factor: 9.319

5.  Interaction of CDP-choline with synaptosomal transport of biogenic amines and their precursors in vitro and in vivo in the rat corpus striatum.

Authors:  M Martinet; P Fonlupt; H Pacheco
Journal:  Experientia       Date:  1978-09-15

6.  Effect of oral CDP-choline on plasma choline and uridine levels in humans.

Authors:  R J Wurtman; M Regan; I Ulus; L Yu
Journal:  Biochem Pharmacol       Date:  2000-10-01       Impact factor: 5.858

7.  Profile of nucleotides and nucleosides of human milk.

Authors:  M Sugawara; N Sato; T Nakano; T Idota; I Nakajima
Journal:  J Nutr Sci Vitaminol (Tokyo)       Date:  1995-08       Impact factor: 2.000

8.  Effects of cytidine-5' diphosphocholine on norepinephrine, dopamine and serotonin synthesis in various regions of the rat brain.

Authors:  M Martinet; P Fonlupt; H Pacheco
Journal:  Arch Int Pharmacodyn Ther       Date:  1979-05

9.  Molecular evidence for mitochondrial dysfunction in bipolar disorder.

Authors:  Christine Konradi; Molly Eaton; Matthew L MacDonald; John Walsh; Francine M Benes; Stephan Heckers
Journal:  Arch Gen Psychiatry       Date:  2004-03

10.  Brain metabolic alterations in medication-free patients with bipolar disorder.

Authors:  Stephen R Dager; Seth D Friedman; Aimee Parow; Christina Demopulos; Andrew L Stoll; In Kyoon Lyoo; David L Dunner; Perry F Renshaw
Journal:  Arch Gen Psychiatry       Date:  2004-05
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  5 in total

1.  Decreased brain PME/PDE ratio in bipolar disorder: a preliminary (31) P magnetic resonance spectroscopy study.

Authors:  Xian-Feng Shi; Paul J Carlson; Young-Hoon Sung; Kristen K Fiedler; Lauren N Forrest; Tracy L Hellem; Rebekah S Huber; Seong-Eun Kim; Chun Zuo; Eun-Kee Jeong; Perry F Renshaw; Douglas G Kondo
Journal:  Bipolar Disord       Date:  2015-10-19       Impact factor: 6.744

2.  Frontal lobe bioenergetic metabolism in depressed adolescents with bipolar disorder: a phosphorus-31 magnetic resonance spectroscopy study.

Authors:  Xian-Feng Shi; Douglas G Kondo; Young-Hoon Sung; Tracy L Hellem; Kristen K Fiedler; Eun-Kee Jeong; Rebekah S Huber; Perry F Renshaw
Journal:  Bipolar Disord       Date:  2012-07-20       Impact factor: 6.744

Review 3.  Targeting Mitochondrial Dysfunction for Bipolar Disorder.

Authors:  Maya Kuperberg; Sophie L A Greenebaum; Andrew A Nierenberg
Journal:  Curr Top Behav Neurosci       Date:  2021

Review 4.  Comparative efficacy of mitochondrial agents for bipolar disorder during depressive episodes: a network meta-analysis using frequentist and Bayesian approaches.

Authors:  Rituparna Maiti; Archana Mishra; Biswa Ranjan Mishra; Monalisa Jena
Journal:  Psychopharmacology (Berl)       Date:  2021-11-09       Impact factor: 4.415

Review 5.  Mitochondrial Agents for Bipolar Disorder.

Authors:  Círia Pereira; Victor Chavarria; João Vian; Melanie Maree Ashton; Michael Berk; Wolfgang Marx; Olivia May Dean
Journal:  Int J Neuropsychopharmacol       Date:  2018-06-01       Impact factor: 5.176
  5 in total

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