| Literature DB >> 21481815 |
Helen Waller1, Daniel Freeman, Suzanne Jolley, Graham Dunn, Philippa Garety.
Abstract
Delusions are often resistant to change, persisting despite successful antipsychotic treatment or Cognitive Behavioural Therapy. This study aimed to target reasoning processes, particularly the 'Jumping to Conclusions' (JTC) bias and belief flexibility, which are thought to play a part in maintaining delusional conviction. 13 participants with a diagnosis of psychosis and high levels of conviction in their delusions completed a one-off computerised training package, lasting approximately 1.5 h. Outcomes were assessed at baseline, pre-intervention (two weeks later), post-intervention (immediately after completing the training) and at 1 month follow-up. The package was well received by participants. There were improvements in JTC, belief flexibility and delusional conviction between pre- and post-intervention measures. Controlled studies powered to detect changes in key outcomes are warranted in order to evaluate the efficacy of the programme.Entities:
Mesh:
Year: 2011 PMID: 21481815 PMCID: PMC3145959 DOI: 10.1016/j.jbtep.2011.03.001
Source DB: PubMed Journal: J Behav Ther Exp Psychiatry ISSN: 0005-7916
Fig. 1Examples of slides from the Training Programme: Task Four.
Clinical and demographic information: means (SD) and numbers of participants (n = 13).
| Age | 44.6 (10.2) years |
| Sex | 7 Male |
| Ethnicity | 6 (46.2%) White |
| Diagnosis | 7 (53.8%) Schizophrenia |
| Duration of illness | 16.73 (9.1) years |
| Self-reported duration of primary delusion | 13.75 (7.5) years |
| Previous experience of CBT | 12 (92.3%) |
| Medication | 13 (100%) |
| Participants showing the JTC bias | 6 (46.2%) |
| Full scale IQ | 88.93 (16.4) |
| DASS total score | 55.23 (24.02) |
| PANSS positive symptom scale | 22.92 (3.90) |
| PSYRATS total score | 17.77 (2.68) |
Key: DASS = Depression Anxiety Stress Scales; PANSS = Positive and Negative Syndrome Scale; PSYRATS = Psychotic Symptoms Rating Scale.
Mean scores (sd) and numbers of participants on key outcomes across time points.
| Baseline 1 | Baseline 2 | Post-intervention 1 | Post-intervention 2 | |
|---|---|---|---|---|
| Probabilistic reasoning task: mean no. of beads requested (sd) | 4.08 (3.17) | 3.92 (2.81) | 4.69 (3.01) | 5.00 (3.00) |
| Probabilistic reasoning task: number showing JTC bias (% of total) | 6 (46.2%) | 5 (38.5%) | 3 (23.1%) | 3 (23.1%) |
| Mean % conviction (sd) | 99.15 (2.76) | 97.31 (8.32) | 80.77 (31.22) | 85.69 (27.99) |
| Belief flexibility: mean PBM (sd) | 8.65 (11.29) | 13.08 (27.50) | 30.77 (31.48) | 23.85 (22.19) |
| Belief flexibility: no. of participants showing positive RTHC (% of total) | 1 (7.7%) | 3 (23.1%) | 5 (38.5%) | 10 (76.9%) |
| Belief flexibility: number of EoE (% of total) | 2 (15.4%) | 3 (23.1%) | 5 (38.5%) | 6 (46.2%) |
Key: JTC = Jumping to Conclusions; PBM = Possibility of Being Mistaken; RTHC = Reaction to Hypothetical Contradiction; EoE = Belief Flexibility.
Mean Scores (sd) and statistical analysis of key outcomes across baseline and post-intervention periods (n = 13).
| Baseline | Post-intervention | Df | Effect size (Cohen’s d∗) | |||
|---|---|---|---|---|---|---|
| No. of beads requested | 4.00 (2.94) | 4.85 (2.75) | 3.96 | 1, 12 | 0.07 | 0.30 |
| % Conviction | 98.23 (4.62) | 83.23 (18.58) | 8.52 | 1, 12 | 0.01 | 1.06 |
| Belief flexibility: PBM | 10.87 (16.62) | 27.31 (22.04) | 11.07 | 1, 12 | 0.01 | 0.82 |
Key: PBM = Possibility of Being Mistaken.
∗Cohen’s d calculated using group means & pooled SD (Dunlap et al., 1996).
Examples of participant comments on the Training Programme.