Literature DB >> 21481423

Improved midterm outcomes for type A (central) pulmonary emboli treated surgically.

James P Greelish1, Marzia Leacche, Natalia S Solenkova, Rashid M Ahmad, John G Byrne.   

Abstract

OBJECTIVES: We propose a simplified anatomic classification for pulmonary emboli that algorithmically differentiates those who might be best treated with surgical pulmonary embolectomy (type A) from those best treated medically (type B). We hypothesized that patients with type A pulmonary emboli treated with immediate surgical embolectomy demonstrate superior long-term survival compared with patients with type A pulmonary emboli treated medically.
METHODS: Patients admitted between 2002 and 2008 with a diagnosis of pulmonary emboli made based on computed tomographic angiographic imaging (n = 779) were analyzed. Computed tomographic angiographic images were reviewed in a blind fashion, and anatomic classification of emboli was made. Patients with central thrombus, defined by location medial to the lateral mediastinal boundaries (ie, involving the main, primary, or both branch pulmonary arteries), were classified as having type A pulmonary emboli (n = 107), whereas those with peripheral pulmonary emboli located beyond these boundaries were classified as having type B pulmonary emboli (n = 672). Four patients with type A pulmonary emboli treated with catheter embolectomy were excluded from the analysis.
RESULTS: Of the 103 patients with type A pulmonary emboli, 15 (14%) were treated with immediate surgical pulmonary embolectomy, and 88 (85%) were treated medically. Patients with type A pulmonary emboli treated surgically had similar 30-day mortality compared with those treated medically (13% vs 17%, P = .532). At a mean of 24 ± 18 months' follow-up (range, 1-82 months), survival at 1, 3, and 5 years for patients with type A pulmonary emboli treated surgically was significantly better than that in the patients with type A pulmonary emboli treated medically (P = .0001).
CONCLUSIONS: For patients with type A pulmonary emboli, immediate surgical intervention appears to offer superior midterm survival compared with medical treatment alone. Although the medical and surgical groups were substantially different and the differences might have affected survival, this simplified classification for pulmonary emboli might help direct optimal treatment strategies.
Copyright © 2011. Published by Mosby, Inc.

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Year:  2011        PMID: 21481423     DOI: 10.1016/j.jtcvs.2010.12.030

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  9 in total

1.  Surgical embolectomy for acute massive pulmonary embolism.

Authors:  Senol Yavuz; Faruk Toktas; Tugrul Goncu; Cuneyt Eris; Arif Gucu; Derih Ay; Burak Erdolu; Erhan Tenekecioglu; Kemal Karaagac; Hakan Vural; Ahmet Ozyazicioglu
Journal:  Int J Clin Exp Med       Date:  2014-12-15

Review 2.  Surgical embolectomy for acute massive pulmonary embolism: state of the art.

Authors:  Alessandra Iaccarino; Giacomo Frati; Leonardo Schirone; Wael Saade; Elio Iovine; Mizar D'Abramo; Antonio De Bellis; Sebastiano Sciarretta; Ernesto Greco
Journal:  J Thorac Dis       Date:  2018-08       Impact factor: 2.895

3.  Surgical Thrombectomy for Pulmonary Embolism: Updated Performance Rates and Outcomes.

Authors:  Fahad Alqahtani; Muhammad Bilal Munir; Sami Aljohani; Abdul Tarabishy; Ahmad Almustafa; Mohamad Alkhouli
Journal:  Tex Heart Inst J       Date:  2019-06-01

Review 4.  Intervention in Massive Pulmonary Embolus: Catheter Thrombectomy/Thromboaspiration versus Systemic Lysis versus Surgical Thrombectomy.

Authors:  John M Moriarty; Martin Edwards; Adam N Plotnik
Journal:  Semin Intervent Radiol       Date:  2018-06-04       Impact factor: 1.513

5.  Thromboembolism-in-Transit and Patent Foramen Ovale: Should Screening Echocardiogram Be Routine for Thromboembolic Disease?

Authors:  Dawn S Hui; Fernando Fleischman; P Michael McFadden
Journal:  Ochsner J       Date:  2016

6.  Residual pulmonary hypertension after retrograde pulmonary embolectomy: long-term follow-up of 30 patients with massive and submassive pulmonary embolism.

Authors:  Khalil Zarrabi; Abdolali Zolghadrasli; Mohammad Ali Ostovan; Azimeh Azimifar; Leila Malekmakan
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-05-14

7.  Outcome of surgical embolectomy in patients with massive pulmonary embolism with and without cardiopulmonary resuscitation.

Authors:  Reza Hajizadeh; Samad Ghaffari; Afshin Habibzadeh; Naser Safaei; Kamran Mohammadi; Abdolmohammad Ranjbar; Sahar Ghodratizadeh
Journal:  Kardiochir Torakochirurgia Pol       Date:  2017-12-20

Review 8.  Management dilemmas in acute pulmonary embolism.

Authors:  Robin Condliffe; Charlie A Elliot; Rodney J Hughes; Judith Hurdman; Rhona M Maclean; Ian Sabroe; Joost J van Veen; David G Kiely
Journal:  Thorax       Date:  2013-12-16       Impact factor: 9.139

Review 9.  Current Management of Acute Pulmonary Embolism.

Authors:  Carlos R Martinez Licha; Chelsea M McCurdy; Sarina Masso Maldonado; Lawrence S Lee
Journal:  Ann Thorac Cardiovasc Surg       Date:  2019-10-05       Impact factor: 1.520

  9 in total

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