| Literature DB >> 30233892 |
Alessandra Iaccarino1,2, Giacomo Frati1,3, Leonardo Schirone1, Wael Saade4, Elio Iovine1, Mizar D'Abramo4, Antonio De Bellis5, Sebastiano Sciarretta1,3, Ernesto Greco4.
Abstract
Massive pulmonary embolism (PE) is a severe condition that can potentially lead to death caused by right ventricular (RV) failure and the consequent cardiogenic shock. Despite the fact thrombolysis is often administrated to critical patients to increase pulmonary perfusion and to reduce RV afterload, surgical treatment represents another valid option in case of failure or contraindications to thrombolytic therapy. Correct risk stratification and multidisciplinary proactive teams are critical factors to dramatically decrease the mortality of this global health burden. In fact, the worldwide incidence of PE is 60-70 per 100,000, with a mortality ranging from 1% for small PE to 65% for massive PE. This review provides an overview of the diagnosis and management of this highly lethal pathology, with a focus on the surgical approaches at the state of the art.Entities:
Keywords: Acute pulmonary embolism; cerebrovascular disease; surgical embolectomy
Year: 2018 PMID: 30233892 PMCID: PMC6129933 DOI: 10.21037/jtd.2018.07.87
Source DB: PubMed Journal: J Thorac Dis ISSN: 2072-1439 Impact factor: 2.895