Literature DB >> 21480339

Drug-induced cholestasis.

Manmeet S Padda1, Mayra Sanchez, Abbasi J Akhtar, James L Boyer.   

Abstract

Recent progress in understanding the molecular mechanisms of bile formation and cholestasis have led to new insights into the pathogenesis of drug-induced cholestasis. This review summarizes their variable clinical presentations, examines the role of transport proteins in hepatic drug clearance and toxicity, and addresses the increasing importance of genetic determinants, as well as practical aspects of diagnosis and management. 2011 American Association for the Study of Liver Diseases.

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Year:  2011        PMID： 21480339      PMCID： PMC3089004          DOI： 10.1002/hep.24229

Source DB:  PubMed          Journal:  Hepatology        ISSN： 0270-9139            Impact factor:   17.425


  82 in total

Review 1.  Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs.

Authors:  Bradley L Urquhart; Rommel G Tirona; Richard B Kim
Journal:  J Clin Pharmacol       Date:  2007-05       Impact factor: 3.126

2.  Vanishing bile duct and Stevens-Johnson syndrome associated with ciprofloxacin treated with tacrolimus.

Authors:  Gokhan Okan; Serpil Yaylaci; Onder Peker; Sabahattin Kaymakoglu; Murat Saruc
Journal:  World J Gastroenterol       Date:  2008-08-07       Impact factor: 5.742

3.  Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes.

Authors:  Ann K Daly; Guruprasad P Aithal; Julian B S Leathart; Richard A Swainsbury; Tarana Singh Dang; Christopher P Day
Journal:  Gastroenterology       Date:  2006-11-17       Impact factor: 22.682

4.  Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.

Authors:  Carmen Lang; Yvonne Meier; Bruno Stieger; Ulrich Beuers; Thomas Lang; Reinhold Kerb; Gerd A Kullak-Ublick; Peter J Meier; Christiane Pauli-Magnus
Journal:  Pharmacogenet Genomics       Date:  2007-01       Impact factor: 2.089

5.  Functional analysis of a mutation in the SLCO1B1 gene (c.1628T>G) identified in a Japanese patient with pravastatin-induced myopathy.

Authors:  Tomomi Furihata; Naoki Satoh; Tomoharu Ohishi; Miyuki Ugajin; Yoshio Kameyama; Kaori Morimoto; Sayaka Matsumoto; Keiko Yamashita; Kaoru Kobayashi; Kan Chiba
Journal:  Pharmacogenomics J       Date:  2009-02-24       Impact factor: 3.550

6.  Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.

Authors:  Hong Lu; Supratim Choudhuri; Kenichiro Ogura; Iván L Csanaky; Xiaohong Lei; Xingguo Cheng; Pei-zhen Song; Curtis D Klaassen
Journal:  Toxicol Sci       Date:  2008-02-21       Impact factor: 4.849

7.  Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump.

Authors:  Yvonne Meier; Tina Zodan; Carmen Lang; Roland Zimmermann; Gerd A Kullak-Ublick; Peter J Meier; Bruno Stieger; Christiane Pauli-Magnus
Journal:  World J Gastroenterol       Date:  2008-01-07       Impact factor: 5.742

Review 8.  Vanishing bile duct syndrome.

Authors:  Nancy S Reau; Donald M Jensen
Journal:  Clin Liver Dis       Date:  2008-02       Impact factor: 6.126

Review 9.  Human drug hepatotoxicity: a contemporary clinical perspective.

Authors:  David N Assis; Victor J Navarro
Journal:  Expert Opin Drug Metab Toxicol       Date:  2009-05       Impact factor: 4.481

10.  Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy.

Authors:  P H Dixon; S W C van Mil; J Chambers; S Strautnieks; R J Thompson; F Lammert; R Kubitz; V Keitel; A Glantz; L-A Mattsson; H-U Marschall; M Molokhia; G E Moore; K J Linton; C Williamson
Journal:  Gut       Date:  2008-11-05       Impact factor: 23.059
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  88 in total

1.  Mellow Yellow: Diagnosis and Management of Multifactorial Postoperative Jaundice.

Authors:  Apurva Tandon; Andrew K Roorda; Prithvi Legha; Ankur Sangoi; George Triadafilopoulos
Journal:  Dig Dis Sci       Date:  2015-10-30       Impact factor: 3.199

2.  From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.

Authors:  Sreenivasa C Ramaiahgari; Suramya Waidyanatha; Darlene Dixon; Michael J DeVito; Richard S Paules; Stephen S Ferguson
Journal:  Toxicol Sci       Date:  2017-09-01       Impact factor: 4.849

3.  Critical Factors in the Assessment of Cholestatic Liver Injury In Vitro.

Authors:  Benjamin L Woolbright; Hartmut Jaeschke
Journal:  Methods Mol Biol       Date:  2015

Review 4.  A Change in Bile Flow: Looking Beyond Transporter Inhibition in the Development of Drug-induced Cholestasis.

Authors:  Brandy Garzel; Lei Zhang; Shiew-Mei Huang; Hongbing Wang
Journal:  Curr Drug Metab       Date:  2019       Impact factor: 3.731

Review 5.  An updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters.

Authors:  Kyunghee Yang; Kathleen Köck; Alexander Sedykh; Alexander Tropsha; Kim L R Brouwer
Journal:  J Pharm Sci       Date:  2013-05-07       Impact factor: 3.534

6.  Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin.

Authors:  Yonghong Zhang; Da Shi; Ruben Abagyan; Weina Dai; Mingyang Dong
Journal:  Interdiscip Sci       Date:  2019-05-20       Impact factor: 2.233

Review 7.  Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models.

Authors:  Richard J Weaver; Eric A Blomme; Amy E Chadwick; Ian M Copple; Helga H J Gerets; Christopher E Goldring; Andre Guillouzo; Philip G Hewitt; Magnus Ingelman-Sundberg; Klaus Gjervig Jensen; Satu Juhila; Ursula Klingmüller; Gilles Labbe; Michael J Liguori; Cerys A Lovatt; Paul Morgan; Dean J Naisbitt; Raymond H H Pieters; Jan Snoeys; Bob van de Water; Dominic P Williams; B Kevin Park
Journal:  Nat Rev Drug Discov       Date:  2019-11-20       Impact factor: 84.694

8.  Secondary sclerosing cholangitis in a critically ill patient.

Authors:  Krista E Weiss; Juergen K Willmann; R Brooke Jeffrey; Terry S Desser
Journal:  Quant Imaging Med Surg       Date:  2016-04

Review 9.  Secondary Sclerosing Cholangitis in Critically Ill Patients: An Underdiagnosed Entity.

Authors:  Pedro Martins; Mariana Verdelho Machado
Journal:  GE Port J Gastroenterol       Date:  2019-07-30

10.  PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice.

Authors:  Cindy Yanfei Li; Joseph L Dempsey; Dongfang Wang; SooWan Lee; Kris M Weigel; Qiang Fei; Deepak Kumar Bhatt; Bhagwat Prasad; Daniel Raftery; Haiwei Gu; Julia Yue Cui
Journal:  Drug Metab Dispos       Date:  2018-05-16       Impact factor: 3.922
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