BACKGROUND: The aim of this cross-sectional study was to explore the association between echocardiographic parameters and CHADS2 score in patients with nonvalvular atrial fibrillation (AF). METHODS: Seventy-seven subjects (36 patients with AF, 41 control subjects) underwent standard two-dimensional, Doppler, and speckle-tracking echocardiography to compute regional and global left atrial (LA) strain. RESULTS: Global longitudinal LA strain was reduced in patients with AF compared with controls (P < .001) and was a predictor of high risk for thromboembolism (CHADS2 score ≥ 2; odds ratio, 0.86; P = .02). LA strain indexes showed good interobserver and intraobserver variability. In sequential Cox models, the prediction of hospitalization and/or death was improved by addition of global LA strain and indexed LA volume to CHADS2 score (P = .003). CONCLUSIONS: LA strain is a reproducible marker of dynamic LA function and a predictor of stroke risk and cardiovascular outcomes in patients with AF.
BACKGROUND: The aim of this cross-sectional study was to explore the association between echocardiographic parameters and CHADS2 score in patients with nonvalvular atrial fibrillation (AF). METHODS: Seventy-seven subjects (36 patients with AF, 41 control subjects) underwent standard two-dimensional, Doppler, and speckle-tracking echocardiography to compute regional and global left atrial (LA) strain. RESULTS: Global longitudinal LA strain was reduced in patients with AF compared with controls (P < .001) and was a predictor of high risk for thromboembolism (CHADS2 score ≥ 2; odds ratio, 0.86; P = .02). LA strain indexes showed good interobserver and intraobserver variability. In sequential Cox models, the prediction of hospitalization and/or death was improved by addition of global LA strain and indexed LA volume to CHADS2 score (P = .003). CONCLUSIONS: LA strain is a reproducible marker of dynamic LA function and a predictor of stroke risk and cardiovascular outcomes in patients with AF.
Authors: Ahmet Barutçu; Emine Gazi; Ahmet Temiz; Adem Bekler; Burak Altun; Bahadır Kırılmaz; Uğur Küçük Journal: Int J Cardiovasc Imaging Date: 2014-04-22 Impact factor: 2.357
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Authors: Brandon W Calenda; Valentin Fuster; Jonathan L Halperin; Christopher B Granger Journal: Nat Rev Cardiol Date: 2016-07-07 Impact factor: 32.419
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Authors: Gergely Ágoston; Judit Szilágyi; Gábor Bencsik; Cristina Tutuianu; Gergely Klausz; László Sághy; Albert Varga; Tamás Forster; Róbert Pap Journal: J Interv Card Electrophysiol Date: 2015-06-30 Impact factor: 1.900