Literature DB >> 21476775

The chain sucker: translocation dynamics of a polymer chain into a long narrow channel driven by longitudinal flow.

Kaifu Luo1, Ralf Metzler.   

Abstract

Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a narrow channel of width R embedded in two dimensions, driven by a force proportional to the number of monomers in the channel. Such a setup mimics typical experimental situations in nano/microfluidics. During the translocation process if the monomers in the channel can sufficiently quickly assume steady state motion, we observe the scaling τ ∼ N∕F of the translocation time τ with the driving force F per bead and the number N of monomers per chain. With smaller channel width R, steady state motion cannot be achieved, effecting a nonuniversal dependence of τ on N and F. From the simulations we also deduce the waiting time distributions under various conditions for the single segment passage through the channel entrance. For different chain lengths but the same driving force, the curves of the waiting time as a function of the translocation coordinate s feature a maximum located at identical s(max), while with increasing the driving force or the channel width the value of s(max) decreases.

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Year:  2011        PMID: 21476775     DOI: 10.1063/1.3575239

Source DB:  PubMed          Journal:  J Chem Phys        ISSN: 0021-9606            Impact factor:   3.488


  4 in total

1.  Conformation-dependent translocation of a star polymer through a nanochannel.

Authors:  Zhu Liu; Jiannan Liu; Mengying Xiao; Rong Wang; Yeng-Long Chen
Journal:  Biomicrofluidics       Date:  2014-09-10       Impact factor: 2.800

2.  Effects of Polymer Length and Salt Concentration on the Transport of ssDNA in Nanofluidic Channels.

Authors:  Weixin Qian; Kentaro Doi; Satoyuki Kawano
Journal:  Biophys J       Date:  2017-03-14       Impact factor: 4.033

3.  Bandpass filtering of DNA elastic modes using confinement and tension.

Authors:  Jun Lin; Fredrik Persson; Joachim Fritzsche; Jonas O Tegenfeldt; Omar A Saleh
Journal:  Biophys J       Date:  2012-01-03       Impact factor: 4.033

4.  Theoretical study of the transpore velocity control of single-stranded DNA.

Authors:  Weixin Qian; Kentaro Doi; Satoshi Uehara; Kaito Morita; Satoyuki Kawano
Journal:  Int J Mol Sci       Date:  2014-08-11       Impact factor: 5.923

  4 in total

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