AIMS: To study the epidemiology of biopsy proven giant cell arteritis (GCA) in patients in the Otago region, New Zealand. MATERIALS AND METHODS: Records of 363 consecutive patients who underwent temporal artery biopsy at Dunedin Hospital between 1996–2005 were reviewed. Annual incidence of biopsy-proven GCA was estimated, epidemiologic characteristics of the biopsy-positive group was compared with the biopsy-negative group. RESULTS: Among the 363 patients who underwent temporal artery biopsy there were 105 (29%) males and 258 (71%) females; biopsy-proven GCA was diagnosed in 70 (19%) patients. The mean age of biopsy-positive group was 72.8 years (range 57-91 years, SD 8.2), which was comparable to the biopsy-negative group 73.4 years (range 50–97 years, SD 9.5), p<0.2. The mean annual incidence of GCA in Otago was 12.73/100,000 CI (11.7–14.3, p<0.5) for patients ≥50 years over the 9 years of observation. CONCLUSIONS: The first large study of GCA from Australasia demonstrated that a variation in the annual incidence rate for giant cell arteritis in Otago, New Zealand showed a cyclic pattern. The overall incidence seems to reflect the ethnic origins of the majority of the population from Britain.
AIMS: To study the epidemiology of biopsy proven giant cell arteritis (GCA) in patients in the Otago region, New Zealand. MATERIALS AND METHODS: Records of 363 consecutive patients who underwent temporal artery biopsy at Dunedin Hospital between 1996–2005 were reviewed. Annual incidence of biopsy-proven GCA was estimated, epidemiologic characteristics of the biopsy-positive group was compared with the biopsy-negative group. RESULTS: Among the 363 patients who underwent temporal artery biopsy there were 105 (29%) males and 258 (71%) females; biopsy-proven GCA was diagnosed in 70 (19%) patients. The mean age of biopsy-positive group was 72.8 years (range 57-91 years, SD 8.2), which was comparable to the biopsy-negative group 73.4 years (range 50–97 years, SD 9.5), p<0.2. The mean annual incidence of GCA in Otago was 12.73/100,000 CI (11.7–14.3, p<0.5) for patients ≥50 years over the 9 years of observation. CONCLUSIONS: The first large study of GCA from Australasia demonstrated that a variation in the annual incidence rate for giant cell arteritis in Otago, New Zealand showed a cyclic pattern. The overall incidence seems to reflect the ethnic origins of the majority of the population from Britain.
Authors: Dan Pugh; Maira Karabayas; Neil Basu; Maria C Cid; Ruchika Goel; Carl S Goodyear; Peter C Grayson; Stephen P McAdoo; Justin C Mason; Catherine Owen; Cornelia M Weyand; Taryn Youngstein; Neeraj Dhaun Journal: Nat Rev Dis Primers Date: 2022-01-06 Impact factor: 65.038
Authors: Elisabeth De Smit; Linda Clarke; Paul G Sanfilippo; Tony R Merriman; Matthew A Brown; Catherine L Hill; Alex W Hewitt Journal: RMD Open Date: 2017-08-29