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Literature DB >> 21472998

Mathematical models in biology: from molecules to life.

Abstract

A vexing question in the biological sciences is the following: can biological phenotypes be explained with mathematical models of molecules that interact according to physical laws? At the crux of the matter lies the doubt that humans can develop physically faithful mathematical representations of living organisms. We discuss advantages that synthetic biological systems confer that may help us describe life's distinctiveness with tractable mathematics that are grounded on universal laws of thermodynamics and molecular biology.

Entities: Chemical Disease Species

Mesh：

Year: 2011 PMID： 21472998 PMCID： PMC3073512 DOI： 10.1002/wsbm.142

Source DB: PubMed Journal: Wiley Interdiscip Rev Syst Biol Med ISSN： 1939-005X

38 in total

Review 1. Molecular dynamics simulations of biomolecules.

Authors: Martin Karplus; J Andrew McCammon
Journal: Nat Struct Biol Date: 2002-09

2. Genetic regulatory mechanisms in the synthesis of proteins.

Authors: F JACOB; J MONOD
Journal: J Mol Biol Date: 1961-06 Impact factor: 5.469

3. Physicochemical and residue conservation calculations to improve the ranking of protein-protein docking solutions.

Authors: Yuhua Duan; Boojala V B Reddy; Yiannis N Kaznessis
Journal: Protein Sci Date: 2005-02 Impact factor: 6.725

4. Time accelerated Monte Carlo simulations of biological networks using the binomial tau-leap method.

Authors: Abhijit Chatterjee; Kapil Mayawala; Jeremy S Edwards; Dionisios G Vlachos
Journal: Bioinformatics Date: 2005-02-04 Impact factor: 6.937

Review 5. Novel biological networks modulated by complement.

Authors: Dimitrios Mastellos; Christos Andronis; Andreas Persidis; John D Lambris
Journal: Clin Immunol Date: 2005-06 Impact factor: 3.969

6. Computer-aided design of modular protein devices: Boolean AND gene activation.

Authors: H Salis; Y N Kaznessis
Journal: Phys Biol Date: 2006-12-22 Impact factor: 2.583

Review 7. Computational and experimental approaches for modeling gene regulatory networks.

Authors: J Goutsias; N H Lee
Journal: Curr Pharm Des Date: 2007 Impact factor: 3.116

Review 8. Designing biological systems.

Authors: David A Drubin; Jeffrey C Way; Pamela A Silver
Journal: Genes Dev Date: 2007-02-01 Impact factor: 11.361

9. Model reduction of multiscale chemical langevin equations: a numerical case study.

Authors: Vassilios Sotiropoulos; Marie-Nathalie Contou-Carrere; Prodromos Daoutidis; Yiannis N Kaznessis
Journal: IEEE/ACM Trans Comput Biol Bioinform Date: 2009 Jul-Sep Impact factor: 3.710

Review 10. Models for synthetic biology.

Authors: Yiannis N Kaznessis
Journal: BMC Syst Biol Date: 2007-11-06

1 in total

1. proTeOn and proTeOff, new protein devices that inducibly activate bacterial gene expression.

Authors: Katherine Volzing; Konstantinos Biliouris; Yiannis N Kaznessis
Journal: ACS Chem Biol Date: 2011-08-18 Impact factor: 5.100

1 in total