Literature DB >> 21472132

Comparison between surgical outcomes of colorectal cancer in younger and elderly patients.

Longxue Jin1, Norio Inoue, Naoki Sato, Susumu Matsumoto, Hitoshi Kanno, Yuko Hashimoto, Kazuhiro Tasaki, Kinya Sato, Shun Sato, Katsutoshi Kaneko.   

Abstract

AIM: To compare the outcome of surgical treatment of colorectal adenocarcinoma in elderly and younger patients.
METHODS: The outcomes of 122 patients with colorectal adenocarcinoma who underwent surgical treatment between January 2004 and June 2009 were analyzed. The clinicopathological and blood biochemistry data of the younger group (< 75 years) and the elderly group (≥ 75 years) were compared.
RESULTS: There were no significant differences between the two groups in operation time, intraoperative blood loss, hospital stay, time to resumption of oral intake, or morbidity. The elderly group had a significantly higher rate of hypertension and cardiovascular disease. The perioperative serum total protein and albumin levels were significantly lower in the elderly than in the younger group. The serum carcinoembryonic antigen level was lower in the elderly than in the younger group, and there was a significant decreasing trend after the operation in the elderly group.
CONCLUSION: The short-term outcomes of surgical treatment in elderly patients with colorectal adenocarcinoma were acceptable. Surgical treatment in elderly patients was considered a selectively effective approach.

Entities:  

Keywords:  C-reactive protein; Carcinoembryonic antigen; Colorectal tumor; Elderly patient; Morbidity

Mesh:

Substances:

Year:  2011        PMID: 21472132      PMCID: PMC3070137          DOI: 10.3748/wjg.v17.i12.1642

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  19 in total

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2.  Preoperative carcinoembryonic antigen level as a prognostic indicator in colorectal cancer.

Authors:  H J Wanebo; B Rao; C M Pinsky; R G Hoffman; M Stearns; M K Schwartz; H F Oettgen
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3.  Preoperative carcinoembryonic antigen level as an independent prognostic factor in potentially curative colon cancer.

Authors:  Jung Wook Huh; Byung Ryul Oh; Hyeong Rok Kim; Young Jin Kim
Journal:  J Surg Oncol       Date:  2010-04-01       Impact factor: 3.454

Review 4.  Surgery for colorectal cancer in elderly patients: a systematic review. Colorectal Cancer Collaborative Group.

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Journal:  Lancet       Date:  2000-09-16       Impact factor: 79.321

5.  The impact of the risk factor "age" on the early postoperative results of surgery for colorectal carcinoma and its significance for perioperative management.

Authors:  Frank Marusch; Andreas Koch; Uwe Schmidt; Ralf Steinert; Torsten Ueberrueck; Reinhard Bittner; Eugen Berg; Rainer Engemann; Klaus Gellert; Rainer Arbogast; Thomas Körner; Ferdinand Köckerling; Ingo Gastinger; Hans Lippert
Journal:  World J Surg       Date:  2005-08       Impact factor: 3.352

6.  Increase in both CEA and CA19-9 in sera is an independent prognostic indicator in colorectal carcinoma.

Authors:  Tadahiro Nozoe; Tatsuya Rikimaru; Emiko Mori; Toshiro Okuyama; Ikuo Takahashi
Journal:  J Surg Oncol       Date:  2006-08-01       Impact factor: 3.454

7.  Carcinoembryonic antigen and albumin predict survival in patients with advanced colon and rectal cancer.

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8.  Colorectal cancer in the elderly. Is there a role for safe and curative surgery?

Authors:  Giancarlo Basili; Luca Lorenzetti; Graziano Biondi; Enrico Preziuso; Claudio Angrisano; Paolo Carnesecchi; Eugenia Roberto; Orlando Goletti
Journal:  ANZ J Surg       Date:  2008-06       Impact factor: 1.872

9.  Emergency surgery for complicated colorectal carcinoma: a comparison of older and younger patients.

Authors:  José A Alvarez; Ricardo F Baldonedo; Isabel G Bear; Nuria Truán; Gerardo Pire; Paloma Alvarez
Journal:  Int Surg       Date:  2007 Nov-Dec

10.  Elevated CA19-9 as the most significant prognostic factor in advanced colorectal carcinoma.

Authors:  M Kouri; S Pyrhönen; P Kuusela
Journal:  J Surg Oncol       Date:  1992-02       Impact factor: 3.454

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  1 in total

1.  Surgery for colorectal cancer in elderly patients: how can we improve outcome?

Authors:  Henning Mothes; Astrid Bauschke; Silke Schuele; Ekkehard Eigendorff; Annelore Altendorf-Hofmann; Utz Settmacher
Journal:  J Cancer Res Clin Oncol       Date:  2017-05-22       Impact factor: 4.553

  1 in total

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