Literature DB >> 21468913

Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide.

Young-Hee Kim1, Soo-Jin Choo, In-Ja Ryoo, Jong-Seok Ahn, Ick-Dong Yoo.   

Abstract

A new eudesmanolide, 1β,3β-dihydroxy-eudesman-11(13)-en-6α,12-olide (1) was isolated and identified from Taraxacum mongolicum, together with two known compounds, 1β,3β-dihydroxyeudesman-6α,12-olide (2) and loliolide (3). The structure of 1 was established by analysis of its physical and spectroscopic data. 1 was found to have an inhibitory activity on nitric oxide production with an IC(50) of 38.9 μM in activated RAW 264.7 cells.

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Year:  2011        PMID： 21468913     DOI： 10.1007/s12272-011-0104-5

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  6 in total

1.  New 12,8-Eudesmanolides from Eutypella sp. 1-15.

Authors:  Yuezhou Wang; Yue Wang; An-An Wu; Lei Zhang; Zhiyu Hu; Huiying Huang; Qingyan Xu; Xianming Deng
Journal:  J Antibiot (Tokyo)       Date:  2017-07-19       Impact factor: 2.649

2.  Safety and Efficacy of Tien-Hsien Liquid Practical in Patients with Refractory Metastatic Breast Cancer: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase IIa Trial.

Authors:  Wen-Hung Kuo; Chien-An Yao; Chih Hui Lin; King-Jen Chang
Journal:  Evid Based Complement Alternat Med       Date:  2012-04-01       Impact factor: 2.629

3.  High-throughput screen of natural product libraries for hsp90 inhibitors.

Authors:  Jason Davenport; Maurie Balch; Lakshmi Galam; Antwan Girgis; Jessica Hall; Brian S J Blagg; Robert L Matts
Journal:  Biology (Basel)       Date:  2014-02-10

4.  Heme Oxygenase-1 Induction and Anti-inflammatory Actions of Atractylodes macrocephala and Taraxacum herba Extracts Prevented Colitis and Was More Effective than Sulfasalazine in Preventing Relapse.

Authors:  Kyu-Hyun Han; Jong-Min Park; Migyeong Jeong; Young-Min Han; Eun-Jin Go; Juyeon Park; Hocheol Kim; Jae Gab Han; Oran Kwon; Ki Baik Hahm
Journal:  Gut Liver       Date:  2017-09-15       Impact factor: 4.519

5.  Inositol Derivatives and Phenolic Compounds from the Roots of Taraxacum coreanum.

Authors:  Eun Jin Mo; Jong Hoon Ahn; Yang Hee Jo; Seon Beom Kim; Bang Yeon Hwang; Mi Kyeong Lee
Journal:  Molecules       Date:  2017-08-14       Impact factor: 4.411

6.  Anti-Inflammatory Effects and Mechanisms of Dandelion in RAW264.7 Macrophages and Zebrafish Larvae.

Authors:  Wenju Li; Fulong Luo; Xiaohui Wu; Bei Fan; Mingran Yang; Wu Zhong; Dongyan Guan; Fengzhong Wang; Qiong Wang
Journal:  Front Pharmacol       Date:  2022-08-25       Impact factor: 5.988
  6 in total

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