Literature DB >> 21459141

Comment on "Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer," i.e., all we are saying is, give C a chance.

Joseph J Cullen1, Douglas R Spitz, Garry R Buettner.   

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Year:  2011        PMID： 21459141      PMCID： PMC3128375          DOI： 10.1016/j.freeradbiomed.2011.03.030

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN： 0891-5849            Impact factor:   7.376


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  28 in total

1.  Reevaluation of ascorbate in cancer treatment: emerging evidence, open minds and serendipity.

Authors:  S J Padayatty; M Levine
Journal:  J Am Coll Nutr       Date:  2000-08       Impact factor: 3.169

2.  Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas.

Authors:  R White; C Lee; M Anscher; M Gottfried; R Wolff; M Keogan; T Pappas; H Hurwitz; D Tyler
Journal:  Ann Surg Oncol       Date:  1999 Jan-Feb       Impact factor: 5.344

3.  Innovation vs. quality control: an 'unpublishable' clinical trial of supplemental ascorbate in incurable cancer.

Authors:  E Cameron; A Campbell
Journal:  Med Hypotheses       Date:  1991-11       Impact factor: 1.538

4.  Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.

Authors:  M Levine; C Conry-Cantilena; Y Wang; R W Welch; P W Washko; K R Dhariwal; J B Park; A Lazarev; J F Graumlich; J King; L R Cantilena
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

5.  Cancer statistics, 2010.

Authors:  Ahmedin Jemal; Rebecca Siegel; Jiaquan Xu; Elizabeth Ward
Journal:  CA Cancer J Clin       Date:  2010-07-07       Impact factor: 508.702

Review 6.  Thermodynamic and kinetic considerations for the reaction of semiquinone radicals to form superoxide and hydrogen peroxide.

Authors:  Yang Song; Garry R Buettner
Journal:  Free Radic Biol Med       Date:  2010-05-21       Impact factor: 7.376

7.  Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects.

Authors:  Sebastian J Padayatty; Andrew Y Sun; Qi Chen; Michael Graham Espey; Jeanne Drisko; Mark Levine
Journal:  PLoS One       Date:  2010-07-07       Impact factor: 3.240

8.  Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial.

Authors:  E T Creagan; C G Moertel; J R O'Fallon; A J Schutt; M J O'Connell; J Rubin; S Frytak
Journal:  N Engl J Med       Date:  1979-09-27       Impact factor: 91.245

9.  Phase I clinical trial of i.v. ascorbic acid in advanced malignancy.

Authors:  L J Hoffer; M Levine; S Assouline; D Melnychuk; S J Padayatty; K Rosadiuk; C Rousseau; L Robitaille; W H Miller
Journal:  Ann Oncol       Date:  2008-06-09       Impact factor: 32.976

10.  Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.

Authors:  E Cameron; L Pauling
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205
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  4 in total

1.  The latency of peroxisomal catalase in terms of effectiveness factor for pancreatic and glioblastoma cancer cell lines in the presence of high concentrations of H2O2: Implications for the use of pharmacological ascorbate in cancer therapy.

Authors:  Dieanira T Erudaitius; Garry R Buettner; Victor G J Rodgers
Journal:  Free Radic Biol Med       Date:  2020-06-06       Impact factor: 7.376

2.  Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.

Authors:  Xiaodong Ye; Diane Fels; Artak Tovmasyan; Katherine M Aird; Casey Dedeugd; Jennifer L Allensworth; Ivan Kos; Won Park; Ivan Spasojevic; Gayathri R Devi; Mark W Dewhirst; Kam W Leong; Ines Batinic-Haberle
Journal:  Free Radic Res       Date:  2011-09-27

3.  Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer.

Authors:  Christopher M Stephenson; Robert D Levin; Thomas Spector; Christopher G Lis
Journal:  Cancer Chemother Pharmacol       Date:  2013-05-14       Impact factor: 3.333

4.  Extracellular iron diminishes anticancer effects of vitamin C: an in vitro study.

Authors:  Marija Mojić; Jelena Bogdanović Pristov; Danijela Maksimović-Ivanić; David R Jones; Marina Stanić; Sanja Mijatović; Ivan Spasojević
Journal:  Sci Rep       Date:  2014-08-05       Impact factor: 4.379
  4 in total

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