OBJECTIVES: Wound infections after abdominal surgery are still frequent types of nosocomial infections. Suture materials might serve as a vehicle for mechanical transport of bacteria into the surgical wound. To reduce bacterial adherence to surgical sutures, triclosan-coated polyglactin 910 suture materials with antiseptic activity (Vicryl plus®) were developed. The aim of this prospective non-randomized clinical pathway driven study was to ascertain if the use of Vicryl plus® reduced the number of wound infections after transverse laparotomy. PATIENTS AND METHODS: Between October 2003 and October 2007, 839 operations were performed using a transverse abdominal incision. In the first time period, a PDSII® loop suture was used for abdominal wall closure. In the second time period, we used Vicryl plus®. Risk factors were collected prospectively to compare the two groups. RESULTS: Using a PDSII® loop suture for abdominal wall closure in the first time period, 9.2% of the patients developed wound infections. In the second time period, using Vicryl plus®, the number of wound infections decreased to 4.3% (p < 0,005). Both groups were comparable regarding risk factors despite no other changes in protocols of patient care. CONCLUSION: Antiseptic-coated loop Vicryl suture for abdominal wall closure can be superior to PDSII sutures in respect to the development of wound infections after a two-layered closure of transverse laparotomy.
OBJECTIVES: Wound infections after abdominal surgery are still frequent types of nosocomial infections. Suture materials might serve as a vehicle for mechanical transport of bacteria into the surgical wound. To reduce bacterial adherence to surgical sutures, triclosan-coated polyglactin 910 suture materials with antiseptic activity (Vicryl plus®) were developed. The aim of this prospective non-randomized clinical pathway driven study was to ascertain if the use of Vicryl plus® reduced the number of wound infections after transverse laparotomy. PATIENTS AND METHODS: Between October 2003 and October 2007, 839 operations were performed using a transverse abdominal incision. In the first time period, a PDSII® loop suture was used for abdominal wall closure. In the second time period, we used Vicryl plus®. Risk factors were collected prospectively to compare the two groups. RESULTS: Using a PDSII® loop suture for abdominal wall closure in the first time period, 9.2% of the patients developed wound infections. In the second time period, using Vicryl plus®, the number of wound infections decreased to 4.3% (p < 0,005). Both groups were comparable regarding risk factors despite no other changes in protocols of patient care. CONCLUSION: Antiseptic-coated loop Vicryl suture for abdominal wall closure can be superior to PDSII sutures in respect to the development of wound infections after a two-layered closure of transverse laparotomy.
Authors: Walter P Weber; Walter R Marti; Marcel Zwahlen; Heidi Misteli; Rachel Rosenthal; Stefan Reck; Philipp Fueglistaler; Martin Bolli; Andrej Trampuz; Daniel Oertli; Andreas F Widmer Journal: Ann Surg Date: 2008-06 Impact factor: 12.969
Authors: John J Engemann; Yehuda Carmeli; Sara E Cosgrove; Vance G Fowler; Melissa Z Bronstein; Sharon L Trivette; Jane P Briggs; Daniel J Sexton; Keith S Kaye Journal: Clin Infect Dis Date: 2003-02-07 Impact factor: 9.079
Authors: Christoph Justinger; Mohammed Reza Moussavian; Christian Schlueter; Berit Kopp; Otto Kollmar; Martin Karl Schilling Journal: Surgery Date: 2009-01-25 Impact factor: 3.982
Authors: Kuk Hyun Jung; Seung Jong Oh; Kang Kook Choi; Su Mi Kim; Min Gew Choi; Jun Ho Lee; Jae Hyung Noh; Tae Sung Sohn; Jae Moon Bae; Sung Kim Journal: Ann Surg Treat Res Date: 2014-11-28 Impact factor: 1.859
Authors: Ulrike Heger; Sabine Voss; Phillip Knebel; Colette Doerr-Harim; Jens Neudecker; Christoph Schuhmacher; Eugen Faist; Markus K Diener; Meinhard Kieser; Christoph M Seiler; Markus W Büchler Journal: Trials Date: 2011-11-21 Impact factor: 2.279
Authors: Andreas Obermeier; Jochen Schneider; Norbert Harrasser; Jutta Tübel; Heinrich Mühlhofer; Dominik Pförringer; Constantin von Deimling; Peter Foehr; Barbara Kiefel; Christina Krämer; Axel Stemberger; Matthias Schieker; Rainer Burgkart; Rüdiger von Eisenhart-Rothe Journal: PLoS One Date: 2018-01-09 Impact factor: 3.240