Literature DB >> 214513

Specific adsorption of H-2-restricted cytotoxi T cells to macrophage monolayers.

U Kees, A Müllbacher, R V Blanden.   

Abstract

These experiments tested whether Tc cells specific for foreign antigen (X) plus self H-2 adsorbed to macrophage monolayers displaying (a) X with allogeneic H-2; (B) self H-2 alone; (c) X plus self H-2. Specific adsorption occurred only in case (c), a result compatible with altered self and requiring further operational assumptions in dual recognition models.

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Year:  1978        PMID： 214513      PMCID： PMC2185098          DOI： 10.1084/jem.148.6.1711

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  21 in total

1.  Specific elimination of cytotoxic cells. II. Reduction of cytotoxic activity by adsorption on monolayers results from removal of cytotoxic cells and not from inhibition of their activity.

Authors:  J R Neefe; D H Sachs
Journal:  Cell Immunol       Date:  1977-03-01       Impact factor: 4.868

Review 2.  Cell-mediated immunity and the major histocompatibility complex.

Authors:  R E Langman
Journal:  Rev Physiol Biochem Pharmacol       Date:  1978       Impact factor: 5.545

3.  Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

Authors:  H von Boehmer; W Haas; N K Jerne
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

Review 4.  Two different VH gene products make up the T-cell receptors.

Authors:  C A Janeway; H Wigzell; H Binz
Journal:  Scand J Immunol       Date:  1976       Impact factor: 3.487

5.  H-2 antigen-specific cytotoxic T cells induced by concanavalin A: estimation of their relative frequency.

Authors:  M J Bevan; R E Langman; M Cohn
Journal:  Eur J Immunol       Date:  1976-03       Impact factor: 5.532

6.  A dual recognition model for cytotoxic T cells based on thymic selection of precursors with low affinity for Self H-2 antigens.

Authors:  R V Blanden; G L Ada
Journal:  Scand J Immunol       Date:  1978-03       Impact factor: 3.487

7.  Evidence for multiple clones of cytotoxic T cells responding to antigenic determinants on the same molecule.

Authors:  R Geib; C Chiang; J Klein
Journal:  J Immunol       Date:  1978-01       Impact factor: 5.422

8.  Specific immune lysis of paramyxovirus-infected cells by H-2-compatible thymus-derived lymphocytes.

Authors:  P C Doherty; R M Zinkernagel
Journal:  Immunology       Date:  1976-07       Impact factor: 7.397

9.  H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice.

Authors:  R M Zinkernagel
Journal:  J Exp Med       Date:  1976-02-01       Impact factor: 14.307

10.  On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

Authors:  R M Zinkernagel; G N Callahan; A Althage; S Cooper; P A Klein; J Klein
Journal:  J Exp Med       Date:  1978-03-01       Impact factor: 14.307
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  2 in total

1.  Separate cytotoxic T lymphocyte subsets recognize the different H-2 specificities.

Authors:  A Vazquez; C Néauport-Sautès; A Senik
Journal:  J Exp Med       Date:  1980-03-01       Impact factor: 14.307

2.  Idiotypes on major histocompatibility complex-restricted virus-immune cytotoxic T lymphocytes.

Authors:  U R Kees
Journal:  J Exp Med       Date:  1981-06-01       Impact factor: 14.307
  2 in total

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