Literature DB >> 21451134

Winning WNT: race to Wnt signaling inhibitors.

Kazuhide Watanabe1, Xing Dai.   

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Year:  2011        PMID: 21451134      PMCID: PMC3076855          DOI: 10.1073/pnas.1103102108

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  20 in total

Review 1.  Wnt signaling in stem and cancer stem cells.

Authors:  Peter Wend; Jane D Holland; Ulrike Ziebold; Walter Birchmeier
Journal:  Semin Cell Dev Biol       Date:  2010-09-15       Impact factor: 7.727

2.  A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription.

Authors:  Kenneth Ewan; Bozena Pajak; Mark Stubbs; Helen Todd; Olivier Barbeau; Camilo Quevedo; Hannah Botfield; Rodrigo Young; Ruth Ruddle; Lee Samuel; Alysia Battersby; Florence Raynaud; Nicholas Allen; Stephen Wilson; Branko Latinkic; Paul Workman; Edward McDonald; Julian Blagg; Wynne Aherne; Trevor Dale
Journal:  Cancer Res       Date:  2010-07-07       Impact factor: 12.701

Review 3.  Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach.

Authors:  Wei Chen; Minyong Chen; Larry S Barak
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-05-27       Impact factor: 4.052

4.  Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.

Authors:  Curtis A Thorne; Alison J Hanson; Judsen Schneider; Emilios Tahinci; Darren Orton; Christopher S Cselenyi; Kristin K Jernigan; Kelly C Meyers; Brian I Hang; Alex G Waterson; Kwangho Kim; Bruce Melancon; Victor P Ghidu; Gary A Sulikowski; Bonnie LaFleur; Adrian Salic; Laura A Lee; David M Miller; Ethan Lee
Journal:  Nat Chem Biol       Date:  2010-10-03       Impact factor: 15.040

5.  A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis.

Authors:  Wei Wang; Haiyang Liu; Sheng Wang; Xiaojiang Hao; Lin Li
Journal:  Cell Res       Date:  2011-02-15       Impact factor: 25.617

6.  An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.

Authors:  Foster C Gonsalves; Keren Klein; Brittany B Carson; Shauna Katz; Laura A Ekas; Steve Evans; Robert Nagourney; Timothy Cardozo; Anthony M C Brown; Ramanuj DasGupta
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-10       Impact factor: 11.205

7.  A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected].

Authors:  Katayoon H Emami; Cu Nguyen; Hong Ma; Dae Hoon Kim; Kwang Won Jeong; Masakatsu Eguchi; Randall T Moon; Jia-Ling Teo; Se Woong Oh; Hak Yeop Kim; Sung Hwan Moon; Jong Ryul Ha; Michael Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

8.  Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

Authors:  Shih-Min A Huang; Yuji M Mishina; Shanming Liu; Atwood Cheung; Frank Stegmeier; Gregory A Michaud; Olga Charlat; Elizabeth Wiellette; Yue Zhang; Stephanie Wiessner; Marc Hild; Xiaoying Shi; Christopher J Wilson; Craig Mickanin; Vic Myer; Aleem Fazal; Ronald Tomlinson; Fabrizio Serluca; Wenlin Shao; Hong Cheng; Michael Shultz; Christina Rau; Markus Schirle; Judith Schlegl; Sonja Ghidelli; Stephen Fawell; Chris Lu; Daniel Curtis; Marc W Kirschner; Christoph Lengauer; Peter M Finan; John A Tallarico; Tewis Bouwmeester; Jeffery A Porter; Andreas Bauer; Feng Cong
Journal:  Nature       Date:  2009-09-16       Impact factor: 49.962

9.  Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.

Authors:  Maina Lepourcelet; Ying-Nan P Chen; Dennis S France; Huisheng Wang; Phillip Crews; Frank Petersen; Charles Bruseo; Alexander W Wood; Ramesh A Shivdasani
Journal:  Cancer Cell       Date:  2004-01       Impact factor: 31.743

10.  Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15.

Authors:  R Nusse; A van Ooyen; D Cox; Y K Fung; H Varmus
Journal:  Nature       Date:  1984 Jan 12-18       Impact factor: 49.962

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  15 in total

1.  Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin.

Authors:  Shanthi Ganesh; Martin L Koser; Wendy A Cyr; Girish R Chopda; Junyan Tao; Xue Shui; Bo Ying; Dongyu Chen; Purva Pandya; Edmond Chipumuro; Zakir Siddiquee; Kevin Craig; Chengjung Lai; Henryk Dudek; Satdarshan P Monga; Weimin Wang; Bob D Brown; Marc T Abrams
Journal:  Mol Cancer Ther       Date:  2016-07-07       Impact factor: 6.261

2.  Activation of β-catenin signaling is critical for doxorubicin-induced epithelial-mesenchymal transition in BGC-823 gastric cancer cell line.

Authors:  Rongfei Han; Jie Xiong; Ruijing Xiao; Ehtisham Altaf; Jin Wang; Yanping Liu; Hui Xu; Qianshan Ding; Qiuping Zhang
Journal:  Tumour Biol       Date:  2012-10-10

3.  Ubiquitin specific protease 4 positively regulates the WNT/β-catenin signaling in colorectal cancer.

Authors:  Sun-Il Yun; Hyeon Ho Kim; Jung Hwan Yoon; Won Sang Park; Myong-Joon Hahn; Hee Cheol Kim; Chin Ha Chung; Kyeong Kyu Kim
Journal:  Mol Oncol       Date:  2015-07-03       Impact factor: 6.603

4.  Berberine Represses β-Catenin Translation Involving 4E-BPs in Hepatocellular Carcinoma Cells.

Authors:  Kanchan Vishnoi; Rong Ke; Karan S Saini; Navin Viswakarma; Rakesh Sathish Nair; Subhasis Das; Zhengjia Chen; Ajay Rana; Basabi Rana
Journal:  Mol Pharmacol       Date:  2020-10-31       Impact factor: 4.436

Review 5.  Wnt/β-catenin signalling in prostate cancer.

Authors:  Robert M Kypta; Jonathan Waxman
Journal:  Nat Rev Urol       Date:  2012-06-19       Impact factor: 14.432

Review 6.  Prostate cancer progression and metastasis: potential regulatory pathways for therapeutic targeting.

Authors:  Srinivas Nandana; Leland Wk Chung
Journal:  Am J Clin Exp Urol       Date:  2014-07-12

7.  In vitro effects of a small-molecule antagonist of the Tcf/ß-catenin complex on endometrial and endometriotic cells of patients with endometriosis.

Authors:  Sachiko Matsuzaki; Claude Darcha
Journal:  PLoS One       Date:  2013-04-23       Impact factor: 3.240

8.  Embryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targeting.

Authors:  Brian Belyea; Julie Grondin Kephart; Jordan Blum; David G Kirsch; Corinne M Linardic
Journal:  Sarcoma       Date:  2012-04-30

9.  Structural dynamics and inhibitor searching for Wnt-4 protein using comparative computational studies.

Authors:  Mirza A Hammad; Syed Sikander Azam
Journal:  Drug Des Devel Ther       Date:  2015-04-29       Impact factor: 4.162

10.  Prostaglandin E2 promotes survival of naive UCB T cells via the Wnt/β-catenin pathway and alters immune reconstitution after UCBT.

Authors:  L Li; H T Kim; A Nellore; N Patsoukis; V Petkova; S McDonough; I Politikos; S Nikiforow; R Soiffer; J H Antin; K Ballen; C Cutler; J Ritz; V A Boussiotis
Journal:  Blood Cancer J       Date:  2014-01-17       Impact factor: 11.037

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