Literature DB >> 21449934

Intensivist-led management of brain-dead donors is associated with an increase in organ recovery for transplantation.

K Singbartl1, R Murugan, A M Kaynar, D W Crippen, S A Tisherman, K Shutterly, S A Stuart, R Simmons, J M Darby.   

Abstract

The disparity between the number of patients in need of organ transplantation and the number of available organs is steadily rising. We hypothesized that intensivist-led management of brain dead donors would increase the number of organs recovered for transplantation. We retrospectively analyzed data from all consented adult brain dead patients in the year before (n = 35) and after (n = 43) implementation of an intensivist-led donor management program. Donor characteristics before and after implementation were similar. After implementation of the organ donor support team, the overall number of organs recovered for transplantation increased significantly (66 out of 210 potentially available organs vs. 113 out of 258 potentially available organs, p = 0.008). This was largely due to an increase in the number of lungs (8 out of 70 potentially available lungs vs. 21 out of 86 potentially available lungs; p = 0.039) and kidneys (31 out of 70 potentially available kidneys vs. 52 out of 86 potentially available kidneys; p = 0.044) recovered for transplantation. The number of hearts and livers recovered for transplantation did not change significantly. Institution of an intensivist-led organ donor support team may be a new and viable strategy to increase the number of organs available for transplantations. ©2011 The Authors Journal compilation©2011 The American Society of Transplantation and the American Society of Transplant Surgeons.

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Mesh:

Year:  2011        PMID: 21449934     DOI: 10.1111/j.1600-6143.2011.03485.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  16 in total

1.  Mass media campaigns and organ donation: managing conflicting messages and interests.

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Journal:  Med Health Care Philos       Date:  2012-05

2.  Improving the process of deceased organ and tissue donation: a role for donation physicians as specialists.

Authors:  Sam D Shemie; Shavaun MacDonald
Journal:  CMAJ       Date:  2013-12-16       Impact factor: 8.262

Review 3.  The promise of organ and tissue preservation to transform medicine.

Authors:  Sebastian Giwa; Jedediah K Lewis; Luis Alvarez; Robert Langer; Alvin E Roth; George M Church; James F Markmann; David H Sachs; Anil Chandraker; Jason A Wertheim; Martine Rothblatt; Edward S Boyden; Elling Eidbo; W P Andrew Lee; Bohdan Pomahac; Gerald Brandacher; David M Weinstock; Gloria Elliott; David Nelson; Jason P Acker; Korkut Uygun; Boris Schmalz; Brad P Weegman; Alessandro Tocchio; Greg M Fahy; Kenneth B Storey; Boris Rubinsky; John Bischof; Janet A W Elliott; Teresa K Woodruff; G John Morris; Utkan Demirci; Kelvin G M Brockbank; Erik J Woods; Robert N Ben; John G Baust; Dayong Gao; Barry Fuller; Yoed Rabin; David C Kravitz; Michael J Taylor; Mehmet Toner
Journal:  Nat Biotechnol       Date:  2017-06-07       Impact factor: 54.908

4.  Influence of specific thoracic donor therapy on kidney donation and long-term kidney graft survival.

Authors:  María A Ballesteros; Jorge Duerto Álvarez; Luis Martín-Penagos; Emilio Rodrigo; Manuel Arias; Eduardo Miñambres
Journal:  J Nephrol       Date:  2016-11-09       Impact factor: 3.902

Review 5.  Organ donation in adults: a critical care perspective.

Authors:  Giuseppe Citerio; Marcelo Cypel; Geoff J Dobb; Beatriz Dominguez-Gil; Jennifer A Frontera; David M Greer; Alex R Manara; Sam D Shemie; Martin Smith; Franco Valenza; Eelco F M Wijdicks
Journal:  Intensive Care Med       Date:  2016-01-11       Impact factor: 17.440

Review 6.  ICU Management of the Potential Organ Donor: State of the Art.

Authors:  Carolina B Maciel; David M Greer
Journal:  Curr Neurol Neurosci Rep       Date:  2016-09       Impact factor: 5.081

Review 7.  Organ-Protective Intensive Care in Organ Donors.

Authors:  Klaus Hahnenkamp; Klaus Böhler; Heiner Wolters; Karsten Wiebe; Dietmar Schneider; Hartmut H-J Schmidt
Journal:  Dtsch Arztebl Int       Date:  2016-08-22       Impact factor: 5.594

8.  Donor Indocyanine Green Clearance Test Predicts Graft Quality and Early Graft Prognosis After Liver Transplantation.

Authors:  Yunhua Tang; Ming Han; Maogen Chen; Xiaoping Wang; Fei Ji; Qiang Zhao; Zhiheng Zhang; Weiqiang Ju; Dongping Wang; Zhiyong Guo; Xiaoshun He
Journal:  Dig Dis Sci       Date:  2017-09-20       Impact factor: 3.199

9.  Interim results of a national test of the rapid assessment of hospital procurement barriers in donation (RAPiD).

Authors:  H M Traino; G P Alolod; T Shafer; L A Siminoff
Journal:  Am J Transplant       Date:  2012-08-17       Impact factor: 8.086

10.  Organ donation after resuscitation from cardiac arrest.

Authors:  Jonathan Elmer; Bradley J Molyneaux; Kurt Shutterly; Susan A Stuart; Clifton W Callaway; Joseph M Darby; Amy R Weisgerber
Journal:  Resuscitation       Date:  2019-10-22       Impact factor: 5.262

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