Literature DB >> 21448751

Support for a dimensional view of autism spectrum disorders in toddlers.

Lisa D Wiggins1, Diana L Robins, Lauren B Adamson, Roger Bakeman, Christopher C Henrich.   

Abstract

We examined whether clinically distinct subgroups can be derived from a sample of toddlers (n = 186) who failed the Modified Checklist for Autism in Toddlers, received a comprehensive clinical evaluation, and were diagnosed with an autism spectrum disorder (ASD). Three subgroups emerged from cluster analysis distinguished by (a) social, communication, and intellectual skills and (b) the rate and intensity of repetitive behaviors and abnormal sensory response. Preoccupations, compulsions, and rituals did not distinguish resultant subgroups. These results support a dimensional diagnostic view of ASDs in toddlers since subgroup differences were based on symptom severity rather than different symptom profiles. Results also identify specific types and levels of behavioral deficit relevant to toddler populations. Implications for early diagnosis are discussed.

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Year:  2012        PMID: 21448751      PMCID: PMC4387003          DOI: 10.1007/s10803-011-1230-0

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  20 in total

1.  Autism from 2 to 9 years of age.

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Journal:  Arch Gen Psychiatry       Date:  2006-06

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Journal:  J Autism Dev Disord       Date:  2006-10

4.  Association between restricted and repetitive behaviors and nonverbal IQ in children with autism spectrum disorders.

Authors:  Somer L Bishop; Jennifer Richler; Catherine Lord
Journal:  Child Neuropsychol       Date:  2006-08       Impact factor: 2.500

5.  Investigating the structure of the restricted, repetitive behaviours and interests domain of autism.

Authors:  Peter Szatmari; Stelios Georgiades; Susan Bryson; Lonnie Zwaigenbaum; Wendy Roberts; William Mahoney; Jeremy Goldberg; Lawrence Tuff
Journal:  J Child Psychol Psychiatry       Date:  2006-06       Impact factor: 8.982

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Authors:  L C Eaves; H H Ho; D M Eaves
Journal:  J Autism Dev Disord       Date:  1994-02

7.  Using the childhood autism rating scale to diagnose autism spectrum disorders.

Authors:  Colby Chlebowski; James A Green; Marianne L Barton; Deborah Fein
Journal:  J Autism Dev Disord       Date:  2010-07

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Authors:  C Lord; M Rutter; A Le Couteur
Journal:  J Autism Dev Disord       Date:  1994-10

9.  How well does early diagnosis of autism stand the test of time? Follow-up study of children assessed for autism at age 2 and development of an early diagnostic service.

Authors:  Vanessa Moore; Sally Goodson
Journal:  Autism       Date:  2003-03

10.  Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders.

Authors:  Jennifer Richler; Marisela Huerta; Somer L Bishop; Catherine Lord
Journal:  Dev Psychopathol       Date:  2010
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  30 in total

1.  Modeling the phenotypic architecture of autism symptoms from time of diagnosis to age 6.

Authors:  Stelios Georgiades; Michael Boyle; Peter Szatmari; Steven Hanna; Eric Duku; Lonnie Zwaigenbaum; Susan Bryson; Eric Fombonne; Joanne Volden; Pat Mirenda; Isabel Smith; Wendy Roberts; Tracy Vaillancourt; Charlotte Waddell; Teresa Bennett; Mayada Elsabbagh; Ann Thompson
Journal:  J Autism Dev Disord       Date:  2014-12

2.  Combining information from multiple sources for the diagnosis of autism spectrum disorders for toddlers and young preschoolers from 12 to 47 months of age.

Authors:  So Hyun Kim; Catherine Lord
Journal:  J Child Psychol Psychiatry       Date:  2011-09-01       Impact factor: 8.982

3.  Identifying Subgroups of Toddlers with DSM-5 Autism Spectrum Disorder Based on Core Symptoms.

Authors:  Holly K Harris; Collin Lee; Georgios D Sideridis; William J Barbaresi; Elizabeth Harstad
Journal:  J Autism Dev Disord       Date:  2021-01-28

4.  Sensitivity and specificity of proposed DSM-5 criteria for autism spectrum disorder in toddlers.

Authors:  Marianne L Barton; Diana L Robins; Dasal Jashar; Laura Brennan; Deborah Fein
Journal:  J Autism Dev Disord       Date:  2013-05

5.  Categorical versus dimensional approaches to autism-associated intermediate phenotypes in 22q11.2 microdeletion syndrome.

Authors:  Maria Jalbrzikowski; Khwaja Hamzah Ahmed; Arati Patel; Rachel Jonas; Leila Kushan; Carolyn Chow; Carrie E Bearden
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2017-01

6.  Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development.

Authors:  Lisa D Wiggins; Lin H Tian; Susan E Levy; Catherine Rice; Li-Ching Lee; Laura Schieve; Juhi Pandey; Julie Daniels; Lisa Blaskey; Susan Hepburn; Rebecca Landa; Rebecca Edmondson-Pretzel; William Thompson
Journal:  J Autism Dev Disord       Date:  2017-11

7.  Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis.

Authors:  Finale Doshi-Velez; Yaorong Ge; Isaac Kohane
Journal:  Pediatrics       Date:  2013-12-09       Impact factor: 7.124

8.  Screening for Autism in Iranian Preschoolers: Contrasting M-CHAT and a Scale Developed in Iran.

Authors:  Sayyed Ali Samadi; Roy McConkey
Journal:  J Autism Dev Disord       Date:  2015-09

9.  Frequency and pattern of documented diagnostic features and the age of autism identification.

Authors:  Matthew J Maenner; Laura A Schieve; Catherine E Rice; Christopher Cunniff; Ellen Giarelli; Russell S Kirby; Li-Ching Lee; Joyce S Nicholas; Martha S Wingate; Maureen S Durkin
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2013-04       Impact factor: 8.829

10.  Classifying Autism Spectrum Disorders by ADI-R: Subtypes or Severity Gradient?

Authors:  Hannah Cholemkery; Juliane Medda; Thomas Lempp; Christine M Freitag
Journal:  J Autism Dev Disord       Date:  2016-07
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