Autotransplantation of cryopreserved ovarian tissue: a procedure with promise, risks, and a need for a registry.

More and more women are being referred for discussion of fertility preservation options. The ability to efficiently and safely preserve the reproductive potential of thousands of young female cancer patients looks possible, but many issues are not yet resolved. Where is the best place for autotransplantation of ovarian tissue? How long would this tissue be expected to function? What is the chance of hormone production and/or pregnancy from this tissue? What is the risk of recurrent cancer from autotransplantation of ovarian tissue? An accurate assessment of the risks and likelihood of success is critical for appropriately counseling these women.