| Literature DB >> 21447377 |
Shrikant A Survase1, Lalit D Kagliwal, Uday S Annapure, Rekha S Singhal.
Abstract
In present times, the immunosuppressants have gained considerable importance in the world market. Cyclosporin A (CyA) is a cyclic undecapeptide with a variety of biological activities including immunosuppressive, anti-inflammatory, antifungal and antiparasitic properties. CyA is produced by various types of fermentation techniques using Tolypocladium inflatum. In the present review, we discuss the biosynthetic pathway, fermentative production, downstream processing and pharmacological activities of CyA.Entities:
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Year: 2011 PMID： 21447377 DOI： 10.1016/j.biotechadv.2011.03.004
Source DB: PubMed Journal: Biotechnol Adv ISSN： 0734-9750 Impact factor: 14.227