BACKGROUND: Although multiple studies demonstrate benefits of high field imaging of cerebrovasculature, a detailed quantitative analysis of complete cerebrovascular system is unavailable. To compare quality of MR angiography (MRA) acquisitions at various field strengths, we used 3-dimensional (3D) geometric cerebrovascular models extracted from 1.5 T/3 T/7 T scans. METHODS: The 3D cerebrovascular models were compared in volume, length, and number of branches. A relationship between the vascular length and volume was statistically derived. Acquisition performance was benchmarked against the maximum volume at infinitive length. RESULTS: The numbers of vessels discernible on 1.5 T/3 T/7 T are 138/363/907. 3T shows 3.3(1.9) and 7 T 1.2(9.1) times more arteries (veins) than 1.5 T. The vascular lengths and volumes at 1.5 T/3 T/7 T are 3.7/12.5/22.7 m and 15.8/26.6/28.0 cm(3). For arteries: 3T-1.5 T gain is very high in length, high in volume; 7 T-3T gain is medium in length, small in volume. For veins: 3 T-1.5 T gain is moderate in length, high in volume; 7 T-3T gain is very high in length, moderate in volume. 1.5 T shows merely half of vascular volume. At 3 T 6%, while at 7 T only 1% of vascular volume is missing. CONCLUSION: Our approach differs from standard approaches based on visual assessment and signal (contrast)-to-noise ratio. It also measures absolute acquisition performance, provides a unique length-volume relationship, and predicts length/volume for intermediate teslages.
BACKGROUND: Although multiple studies demonstrate benefits of high field imaging of cerebrovasculature, a detailed quantitative analysis of complete cerebrovascular system is unavailable. To compare quality of MR angiography (MRA) acquisitions at various field strengths, we used 3-dimensional (3D) geometric cerebrovascular models extracted from 1.5 T/3 T/7 T scans. METHODS: The 3D cerebrovascular models were compared in volume, length, and number of branches. A relationship between the vascular length and volume was statistically derived. Acquisition performance was benchmarked against the maximum volume at infinitive length. RESULTS: The numbers of vessels discernible on 1.5 T/3 T/7 T are 138/363/907. 3T shows 3.3(1.9) and 7 T 1.2(9.1) times more arteries (veins) than 1.5 T. The vascular lengths and volumes at 1.5 T/3 T/7 T are 3.7/12.5/22.7 m and 15.8/26.6/28.0 cm(3). For arteries: 3T-1.5 T gain is very high in length, high in volume; 7 T-3T gain is medium in length, small in volume. For veins: 3 T-1.5 T gain is moderate in length, high in volume; 7 T-3T gain is very high in length, moderate in volume. 1.5 T shows merely half of vascular volume. At 3 T 6%, while at 7 T only 1% of vascular volume is missing. CONCLUSION: Our approach differs from standard approaches based on visual assessment and signal (contrast)-to-noise ratio. It also measures absolute acquisition performance, provides a unique length-volume relationship, and predicts length/volume for intermediate teslages.
Authors: D R Buis; J C J Bot; F Barkhof; D L Knol; F J Lagerwaard; B J Slotman; W P Vandertop; R van den Berg Journal: AJNR Am J Neuroradiol Date: 2011-11-17 Impact factor: 3.825
Authors: Karsten H Wrede; Philipp Dammann; Sören Johst; Christoph Mönninghoff; Marc Schlamann; Stefan Maderwald; I Erol Sandalcioglu; Mark E Ladd; Michael Forsting; Ulrich Sure; Lale Umutlu Journal: Eur Radiol Date: 2015-06-17 Impact factor: 5.315
Authors: Susan N Wright; Peter Kochunov; Fernando Mut; Maurizio Bergamino; Kerry M Brown; John C Mazziotta; Arthur W Toga; Juan R Cebral; Giorgio A Ascoli Journal: Neuroimage Date: 2013-05-28 Impact factor: 6.556
Authors: Karsten H Wrede; Philipp Dammann; Christoph Mönninghoff; Sören Johst; Stefan Maderwald; I Erol Sandalcioglu; Oliver Müller; Neriman Özkan; Mark E Ladd; Michael Forsting; Marc U Schlamann; Ulrich Sure; Lale Umutlu Journal: PLoS One Date: 2014-01-06 Impact factor: 3.240
Authors: Sören Johst; Stephan Orzada; Anja Fischer; Lena C Schäfer; Kai Nassenstein; Lale Umutlu; Thomas C Lauenstein; Mark E Ladd; Stefan Maderwald Journal: PLoS One Date: 2014-01-16 Impact factor: 3.240
Authors: Karsten H Wrede; Sören Johst; Philipp Dammann; Neriman Özkan; Christoph Mönninghoff; Markus Kraemer; Stefan Maderwald; Mark E Ladd; Ulrich Sure; Lale Umutlu; Marc Schlamann Journal: PLoS One Date: 2014-09-18 Impact factor: 3.240