Literature DB >> 21440203

Lactate: biomarker and potential therapeutic target.

Okorie Nduka Okorie1, Phil Dellinger.   

Abstract

Lactate levels are frequently elevated in critically ill patients and correlate well with disease severity. Elevated lactate levels are prognostic in prehospital, emergency department, and intensive care unit settings. This review discusses the role of lactate as a biomarker in diagnosing and assessing the severity of systemic hypoperfusion, as well as the role of serum lactate measurements in guiding clinical care and enabling prognosis in critically ill patients.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21440203     DOI： 10.1016/j.ccc.2010.12.013

Source DB:  PubMed          Journal:  Crit Care Clin        ISSN： 0749-0704            Impact factor:   3.598


  38 in total

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Review 2.  Lactate as a hemodynamic marker in the critically ill.

Authors:  Brian M Fuller; R Phillip Dellinger
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Review 3.  Lactate cross-talk in host-pathogen interactions.

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4.  Predictive value of lactate in unselected critically ill patients: an analysis using fractional polynomials.

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8.  Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item: a multi-national evaluation.

Authors:  H Bryant Nguyen; Win Sen Kuan; Michael Batech; Pinak Shrikhande; Malcolm Mahadevan; Chih-Huang Li; Sumit Ray; Anna Dengel
Journal:  Crit Care       Date:  2011-09-27       Impact factor: 9.097

9.  A DNA-mediated crosslinking strategy to enhance cellular delivery and sensor performance of protein spherical nucleic acids.

Authors:  Jing Yan; Ya-Ling Tan; Min-Jie Lin; Hang Xing; Jian-Hui Jiang
Journal:  Chem Sci       Date:  2020-12-08       Impact factor: 9.825

10.  Developing a Novel Scoring System for Risk Stratification in Living Donor Liver Transplantation.

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Journal:  J Clin Med       Date:  2021-05-08       Impact factor: 4.241
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