Literature DB >> 21432942

The GeneInsight Suite: a platform to support laboratory and provider use of DNA-based genetic testing.

Samuel J Aronson1, Eugene H Clark, Lawrence J Babb, Samantha Baxter, Lisa M Farwell, Birgit H Funke, Amy Lovelette Hernandez, Victoria A Joshi, Elaine Lyon, Andrew R Parthum, Franklin J Russell, Matthew Varugheese, Thomas C Venman, Heidi L Rehm.   

Abstract

The future of personalized medicine will hinge on effective management of patient genetic profiles. Molecular diagnostic testing laboratories need to track knowledge surrounding an increasingly large number of genetic variants, incorporate this knowledge into interpretative reports, and keep ordering clinicians up to date as this knowledge evolves. Treating clinicians need to track which variants have been identified in each of their patients along with the significance of these variants. The GeneInsight(SM) Suite assists in these areas. The suite also provides a basis for interconnecting laboratories and clinicians in a manner that increases the scalability of personalized medicine processes.
© 2011 Wiley-Liss, Inc.

Entities:  

Mesh：

Year:  2011        PMID： 21432942      PMCID： PMC3082613          DOI： 10.1002/humu.21470

Source DB:  PubMed          Journal:  Hum Mutat        ISSN： 1059-7794            Impact factor:   4.878


  45 in total

Review 1.  Advances in the Molecular Analysis of Soft Tissue Tumors and Clinical Implications.

Authors:  Adrian Marino-Enriquez
Journal:  Surg Pathol Clin       Date:  2015-09

2.  Evaluation: A Qualitative Pilot Study of Novel Information Technology Infrastructure to Communicate Genetic Variant Updates.

Authors:  Stephanie Klinkenberg-Ramirez; Pamela M Neri; Lynn A Volk; Sara J Samaha; Lisa P Newmark; Stephanie Pollard; Matthew Varugheese; Samantha Baxter; Samuel J Aronson; Heidi L Rehm; David W Bates
Journal:  Appl Clin Inform       Date:  2016-06-01       Impact factor: 2.342

3.  A taste of individualized medicine: physicians' reactions to automated genetic interpretations.

Authors:  Hallvard Lærum; Sara Bremer; Stein Bergan; Thomas Grünfeld
Journal:  J Am Med Inform Assoc       Date:  2013-09-03       Impact factor: 4.497

4.  A novel clinician interface to improve clinician access to up-to-date genetic results.

Authors:  Allison R Wilcox; Pamela M Neri; Lynn A Volk; Lisa P Newmark; Eugene H Clark; Lawrence J Babb; Matthew Varugheese; Samuel J Aronson; Heidi L Rehm; David W Bates
Journal:  J Am Med Inform Assoc       Date:  2013-09-07       Impact factor: 4.497

5.  Rates of Actionable Genetic Findings in Individuals with Colorectal Cancer or Polyps Ascertained from a Community Medical Setting.

Authors:  Adam S Gordon; Elisabeth A Rosenthal; David S Carrell; Laura M Amendola; Michael O Dorschner; Aaron Scrol; Ian B Stanaway; Shannon DeVange; James D Ralston; Hana Zouk; Heidi L Rehm; Eric Larson; David R Crosslin; Kathy A Leppig; Gail P Jarvik
Journal:  Am J Hum Genet       Date:  2019-08-15       Impact factor: 11.025

6.  Integration of an OWL-DL knowledge base with an EHR prototype and providing customized information.

Authors:  Xia Jing; Stephen Kay; Tom Marley; Nicholas R Hardiker
Journal:  J Med Syst       Date:  2014-07-06       Impact factor: 4.460

7.  ARBoR: an identity and security solution for clinical reporting.

Authors:  Eric Venner; Mullai Murugan; Walker Hale; Jordan M Jones; Shan Lu; Victoria Yi; Richard A Gibbs
Journal:  J Am Med Inform Assoc       Date:  2019-11-01       Impact factor: 4.497

8.  Analyzing and Reanalyzing the Genome: Findings from the MedSeq Project.

Authors:  Kalotina Machini; Ozge Ceyhan-Birsoy; Danielle R Azzariti; Himanshu Sharma; Peter Rossetti; Lisa Mahanta; Laura Hutchinson; Heather McLaughlin; Robert C Green; Matthew Lebo; Heidi L Rehm
Journal:  Am J Hum Genet       Date:  2019-06-27       Impact factor: 11.025

Review 9.  Clinical analysis and interpretation of cancer genome data.

Authors:  Eliezer M Van Allen; Nikhil Wagle; Mia A Levy
Journal:  J Clin Oncol       Date:  2013-04-15       Impact factor: 44.544

10.  Using Workflow Modeling to Identify Areas to Improve Genetic Test Processes in the University of Maryland Translational Pharmacogenomics Project.

Authors:  Elizabeth M Cutting; Casey L Overby; Meghan Banchero; Toni Pollin; Mark Kelemen; Alan R Shuldiner; Amber L Beitelshees
Journal:  AMIA Annu Symp Proc       Date:  2015-11-05
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.