Literature DB >> 21431191

Pin-point chemical modification of RNA with diverse molecules through the functionality transfer reaction and the copper-catalyzed azide-alkyne cycloaddition reaction.

Kazumitsu Onizuka1, Atsushi Shibata, Yosuke Taniguchi, Shigeki Sasaki.   

Abstract

The internal modification of RNA has been successfully achieved by the functionality transfer reaction (FTR) and following click chemistry with diverse azide compounds. The benefits of the FTR have been demonstrated by its specificity, rapidity, broad applicability, and procedure simplicity. © The Royal Society of Chemistry 2011

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Year:  2011        PMID: 21431191     DOI: 10.1039/c1cc10582e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  8 in total

Review 1.  Novel modifications in RNA.

Authors:  Kelly Phelps; Alexi Morris; Peter A Beal
Journal:  ACS Chem Biol       Date:  2011-12-23       Impact factor: 5.100

2.  C2'-pyrene-functionalized triazole-linked DNA: universal DNA/RNA hybridization probes.

Authors:  Sujay P Sau; Patrick J Hrdlicka
Journal:  J Org Chem       Date:  2011-11-16       Impact factor: 4.354

3.  Enzymatic incorporation of an azide-modified UTP analog into oligoribonucleotides for post-transcriptional chemical functionalization.

Authors:  Harita Rao; Arun A Tanpure; Anupam A Sawant; Seergazhi G Srivatsan
Journal:  Nat Protoc       Date:  2012-05-10       Impact factor: 13.491

4.  Remarkable acceleration of a DNA/RNA inter-strand functionality transfer reaction to modify a cytosine residue: the proximity effect via complexation with a metal cation.

Authors:  Daichi Jitsuzaki; Kazumitsu Onizuka; Atsushi Nishimoto; Ikuya Oshiro; Yosuke Taniguchi; Shigeki Sasaki
Journal:  Nucleic Acids Res       Date:  2014-06-23       Impact factor: 16.971

Review 5.  Labeling and sequencing nucleic acid modifications using bio-orthogonal tools.

Authors:  Hui Liu; Yafen Wang; Xiang Zhou
Journal:  RSC Chem Biol       Date:  2022-06-22

Review 6.  Triazole-Modified Nucleic Acids for the Application in Bioorganic and Medicinal Chemistry.

Authors:  Dagmara Baraniak; Jerzy Boryski
Journal:  Biomedicines       Date:  2021-05-31

7.  Click modification of RNA at adenosine: structure and reactivity of 7-ethynyl- and 7-triazolyl-8-aza-7-deazaadenosine in RNA.

Authors:  Kelly J Phelps; José M Ibarra-Soza; Kiet Tran; Andrew J Fisher; Peter A Beal
Journal:  ACS Chem Biol       Date:  2014-06-16       Impact factor: 5.100

Review 8.  Chemical architecture and applications of nucleic acid derivatives containing 1,2,3-triazole functionalities synthesized via click chemistry.

Authors:  Tim Efthymiou; Wei Gong; Jean-Paul Desaulniers
Journal:  Molecules       Date:  2012-10-26       Impact factor: 4.411

  8 in total

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