INTRODUCTION: Pain is one of the most common non motor symptoms in patients with Parkinson's disease (PD). However, it is underrecognized. We examine the prevalence of pain, characteristics, associated factors, and relation with quality of life and autonomy in a consecutive series of PD patients. PATIENTS AND METHODS: Pain was identified according to International Association for the Study of Pain. Brief Pain Inventory and Medical Outcomes Study 36-Item Short Form were used. RESULTS: Of the 159 patients (72.31 ± 8.83 years; 51.3% female), 115 (72.3%) presented pain. Of these, 51.3% reported pain onset before PD-diagnosis, 27.8% two or more pain types, and 53% PD-related pain. Musculoskeletal (74.8%) and radicular-neuropathic (24.3%) were the types of pain most frequent. The 37.4% of the patients with pain did not received analgesic treatment. Depression was an independent predictor of pain (OR = 7.82; 95% CI = 1.151-53.183; p = 0.035). Pain was an independent predictor of worst quality of life (PDQ-39; regression coefficient: 25.53; standard error: 11.852; 95% CI = 1.48-49.57; p = 0.03) and lower autonomy (Schwab and England; regression coefficient: -13.85; standard error: 6.327; 95% CI = -26.58 to -1.2; p = 0.034). CONCLUSIONS: Pain is very frequent in PD patients. It is associated with depression, and predicts a worst quality of life and lower autonomy for the patient.
INTRODUCTION:Pain is one of the most common non motor symptoms in patients with Parkinson's disease (PD). However, it is underrecognized. We examine the prevalence of pain, characteristics, associated factors, and relation with quality of life and autonomy in a consecutive series of PDpatients. PATIENTS AND METHODS: Pain was identified according to International Association for the Study of Pain. Brief Pain Inventory and Medical Outcomes Study 36-Item Short Form were used. RESULTS: Of the 159 patients (72.31 ± 8.83 years; 51.3% female), 115 (72.3%) presented pain. Of these, 51.3% reported pain onset before PD-diagnosis, 27.8% two or more pain types, and 53% PD-related pain. Musculoskeletal (74.8%) and radicular-neuropathic (24.3%) were the types of pain most frequent. The 37.4% of the patients with pain did not received analgesic treatment. Depression was an independent predictor of pain (OR = 7.82; 95% CI = 1.151-53.183; p = 0.035). Pain was an independent predictor of worst quality of life (PDQ-39; regression coefficient: 25.53; standard error: 11.852; 95% CI = 1.48-49.57; p = 0.03) and lower autonomy (Schwab and England; regression coefficient: -13.85; standard error: 6.327; 95% CI = -26.58 to -1.2; p = 0.034). CONCLUSIONS:Pain is very frequent in PDpatients. It is associated with depression, and predicts a worst quality of life and lower autonomy for the patient.
Authors: Peter Valkovic; Michal Minar; Helena Singliarova; Jan Harsany; Marta Hanakova; Jana Martinkova; Jan Benetin Journal: PLoS One Date: 2015-08-26 Impact factor: 3.240
Authors: Houyam Tibar; Khalil El Bayad; Ahmed Bouhouche; El Hachmia Ait Ben Haddou; Ali Benomar; Mohamed Yahyaoui; Abdelhamid Benazzouz; Wafa Regragui Journal: Front Neurol Date: 2018-04-04 Impact factor: 4.003
Authors: Veit Mylius; Daniel Ciampi de Andrade; Rubens Gisbert Cury; Michael Teepker; Uwe Ehrt; Karla Maria Eggert; Serafin Beer; Jürg Kesselring; Maria Stamelou; Wolfgang H Oertel; Jens Carsten Möller; Jean-Pascal Lefaucheur Journal: Mov Disord Clin Pract Date: 2015-08-09