Literature DB >> 21424974

Dietary flavonoids as cancer prevention agents.

Hua Yao1, Weizheng Xu, Xianglin Shi, Zhuo Zhang.   

Abstract

Dietary agents identified from fruits and vegetables contribute to keeping balanced cell proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other components such as various vitamins, play an important role in cancer prevention. Flavonoids act on reactive oxygen species, cell signal transduction pathways related to cellular proliferation, apoptosis, and angiogenesis. Many studies demonstrate that flavonoids are responsible for chemoprevention, although mechanisms of action remain to be investigated. Overall, exciting data show that dietary flavonoids could be considered as a useful cancer preventive approach. This review summarizes recent advancements on potential cancer preventive effects and mechanic insight of dietary flavonoids.

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Year:  2011        PMID： 21424974     DOI： 10.1080/10590501.2011.551317

Source DB:  PubMed          Journal:  J Environ Sci Health C Environ Carcinog Ecotoxicol Rev        ISSN： 1059-0501            Impact factor:   3.781


  31 in total

1.  Anticarcinogenic action of quercetin by downregulation of phosphatidylinositol 3-kinase (PI3K) and protein kinase C (PKC) via induction of p53 in hepatocellular carcinoma (HepG2) cell line.

Authors:  Akhilendra Kumar Maurya; Manjula Vinayak
Journal:  Mol Biol Rep       Date:  2015-08-27       Impact factor: 2.316

2.  Curcumin loaded self assembled lipid-biopolymer nanoparticles for functional food applications.

Authors:  Lokesh Pathak; Abhinav Kanwal; Yadvendra Agrawal
Journal:  J Food Sci Technol       Date:  2015-02-17       Impact factor: 2.701

3.  Hispidulin induces mitochondrial apoptosis in acute myeloid leukemia cells by targeting extracellular matrix metalloproteinase inducer.

Authors:  Hui Gao; Yongji Liu; Kan Li; Tianhui Wu; Jianjun Peng; Fanbo Jing
Journal:  Am J Transl Res       Date:  2016-02-15       Impact factor: 4.060

4.  Bifunctional chemopreventive effects of Adenocaulon himalaicum through induction of detoxification enzymes and apoptosis.

Authors:  Ji Ho Yun; Saet Byoul Lee; Kyungsu Kang; Eun Ha Lee; Hee Ju Lee; Sang Hoon Jung; Chu Won Nho
Journal:  J Med Food       Date:  2013-08       Impact factor: 2.786

5.  Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

Authors:  Lalitha Ramachandran; Kanjoormana Aryan Manu; Muthu K Shanmugam; Feng Li; Kodappully Sivaraman Siveen; Shireen Vali; Shweta Kapoor; Taher Abbasi; Rohit Surana; Duane T Smoot; Hassan Ashktorab; Patrick Tan; Kwang Seok Ahn; Chun Wei Yap; Alan Prem Kumar; Gautam Sethi
Journal:  J Biol Chem       Date:  2012-09-19       Impact factor: 5.157

Review 6.  Molecular mechanisms of flavonoids in melanin synthesis and the potential for the prevention and treatment of melanoma.

Authors:  Feng Liu-Smith; Frank L Meyskens
Journal:  Mol Nutr Food Res       Date:  2016-03-21       Impact factor: 5.914

7.  Flavonoids from each of the six structural groups reactivate BRM, a possible cofactor for the anticancer effects of flavonoids.

Authors:  Bhaskar Kahali; Stefanie B Marquez; Kenneth W Thompson; Jinlong Yu; Sarah J B Gramling; Li Lu; Aaron Aponick; David Reisman
Journal:  Carcinogenesis       Date:  2014-05-29       Impact factor: 4.944

8.  Pretreatment dietary patterns, weight status, and head and neck squamous cell carcinoma prognosis.

Authors:  Anna E Arthur; Karen E Peterson; Laura S Rozek; Jeremy M G Taylor; Emily Light; Douglas B Chepeha; James R Hébert; Jeffrey E Terrell; Gregory T Wolf; Sonia A Duffy
Journal:  Am J Clin Nutr       Date:  2012-12-26       Impact factor: 7.045

9.  Mixed ligand complexes of Co(II), Ni(II) and Cu(II) with quercetin and diimine ligands: synthesis, characterization, anti-cancer and anti-oxidant activity.

Authors:  Hasene Mutlu Gençkal; Merve Erkisa; Pınar Alper; Saliha Sahin; Engin Ulukaya; Ferda Ari
Journal:  J Biol Inorg Chem       Date:  2019-12-12       Impact factor: 3.358

10.  Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways.

Authors:  Poyil Pratheeshkumar; Amit Budhraja; Young-Ok Son; Xin Wang; Zhuo Zhang; Songze Ding; Lei Wang; Andrew Hitron; Jeong-Chae Lee; Mei Xu; Gang Chen; Jia Luo; Xianglin Shi
Journal:  PLoS One       Date:  2012-10-18       Impact factor: 3.240
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