Literature DB >> 21422992

Impact and feasibility of a comprehensive geriatric assessment in the oncology setting: a pilot study.

Anne M Horgan1, Natasha B Leighl, Linda Coate, Geoffrey Liu, Prakruthi Palepu, Jennifer J Knox, Nicole Perera, Marjan Emami, Shabbir M H Alibhai.   

Abstract

OBJECTIVES: A comprehensive geriatric assessment (CGA) is an objective means of assessing the global health of older patients. While evidence suggesting its promise in improving outcome prediction in the oncology setting is growing, its benefit in guiding treatment decisions remains uncertain. We sought to determine the feasibility and impact of CGA, from a consultative geriatric-oncology service, on treatment decisions in older cancer patients.
METHODS: A pilot clinic, where patients underwent CGA with a medical oncologist and geriatrician, was established. Patients ≥70 years, with gastrointestinal or lung cancer were eligible. Following standard assessment by the primary oncologist, a treatment decision was recorded. Patients subsequently underwent a CGA. The final treatment plan was made by the primary oncologist after receipt of findings and recommendations from the CGA. Changes in treatment decisions were recorded.
RESULTS: The study enrolled from January to October 2009. Of 168 eligible patients, 120 (71%) were not referred for assessment. Thirty of 48 patients approached underwent CGA. In six patients the treatment plan was undecided at time of referral. In five of these, CGA impacted the ultimate decision (83%). Where the management plan was decided at time of referral (n=24), CGA impacted the final decision in only 1 patient (4%). Previously unidentified medical problems were identified in 70% of patients.
CONCLUSIONS: Several factors limited the feasibility of a consultation-type geriatric-oncology service to assess older cancer patients. The impact of CGA in informing treatment decisions was modest but may be of value when the initial treatment decision is uncertain.

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Mesh:

Year:  2012        PMID: 21422992     DOI: 10.1097/COC.0b013e318210f9ce

Source DB:  PubMed          Journal:  Am J Clin Oncol        ISSN: 0277-3732            Impact factor:   2.339


  28 in total

Review 1.  Polypharmacy and potentially inappropriate medication use in geriatric oncology.

Authors:  Manvi Sharma; Kah Poh Loh; Ginah Nightingale; Supriya G Mohile; Holly M Holmes
Journal:  J Geriatr Oncol       Date:  2016-08-03       Impact factor: 3.599

2.  Models of Care in Geriatric Oncology.

Authors:  A Magnuson; W Dale; S Mohile
Journal:  Curr Geriatr Rep       Date:  2014-09

3.  Expert consensus panel guidelines on geriatric assessment in oncology.

Authors:  A O'Donovan; S G Mohile; M Leech
Journal:  Eur J Cancer Care (Engl)       Date:  2015-03-11       Impact factor: 2.520

4.  Research priorities in geriatric oncology for 2013 and beyond.

Authors:  Supriya Mohile; William Dale; Allison Magnuson; Nayana Kamath; Arti Hurria
Journal:  Cancer Forum       Date:  2013-11

Review 5.  How to implement a geriatric assessment in your clinical practice.

Authors:  Schroder Sattar; Shabbir M H Alibhai; Hans Wildiers; Martine T E Puts
Journal:  Oncologist       Date:  2014-09-03

6.  Malnutrition, frailty, and sarcopenia in pancreatic cancer patients: assessments and interventions for the pancreatic surgeon.

Authors:  Noah S Rozich; Caitlin E Jones; Katherine T Morris
Journal:  Ann Pancreat Cancer       Date:  2019-03-11

7.  A randomized phase II trial of geriatric assessment and management for older cancer patients.

Authors:  Martine T E Puts; Schroder Sattar; Michael Kulik; Mary Ellen MacDonald; Kara McWatters; Katherine Lee; Sarah Brennenstuhl; Raymond Jang; Eitan Amir; Monika K Krzyzanowska; Anthony M Joshua; Johanne Monette; Doreen Wan-Chow-Wah; Shabbir M H Alibhai
Journal:  Support Care Cancer       Date:  2017-07-25       Impact factor: 3.603

Review 8.  Incorporating Geriatric Medicine Providers into the Care of the Older Adult with Cancer.

Authors:  Allison Magnuson; Beverly Canin; G J van Londen; Beatrice Edwards; Pamela Bakalarski; Ira Parker
Journal:  Curr Oncol Rep       Date:  2016-11       Impact factor: 5.075

Review 9.  Medical Treatment in Elderly Patients with Non-Small Cell Lung Cancer.

Authors:  Kamila Bakirhan; Janaki Sharma; Roman Perez-Soler; Haiying Cheng
Journal:  Curr Treat Options Oncol       Date:  2016-03

10.  Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial.

Authors:  Anne M Horgan; Bostjan Seruga; Greg R Pond; Shabbir M Alibhai; Eitan Amir; Ronald De Wit; Mario A Eisenberger; Ian F Tannock
Journal:  J Geriatr Oncol       Date:  2014-01-02       Impact factor: 3.599

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