Literature DB >> 21422218

Antimicrobial peptoids are effective against Pseudomonas aeruginosa biofilms.

Rinki Kapoor1, Mayken W Wadman, Michelle T Dohm, Ann M Czyzewski, Alfred M Spormann, Annelise E Barron.   

Abstract

The resistance of biofilms to conventional antibiotics complicates the treatment of chronic cystic fibrosis (CF). We investigated the effects of peptoids, peptides, and conventional antibiotics on the biomass and cell viability within Pseudomonas aeruginosa biofilms. At their MICs, peptoids 1 and 1-C13(4mer) caused maximum reductions in biomass and cell viability, respectively. These results suggest that peptoids of this class could be worth exploring for the treatment of pulmonary infections occurring in CF patients.

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Year:  2011        PMID： 21422218      PMCID： PMC3101385          DOI： 10.1128/AAC.01516-10

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  27 in total

1.  Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment.

Authors:  Robert E. W. Hancock; David P. Speert
Journal:  Drug Resist Updat       Date:  2000-08       Impact factor: 18.500

Review 2.  Mimicry of bioactive peptides via non-natural, sequence-specific peptidomimetic oligomers.

Authors:  James A Patch; Annelise E Barron
Journal:  Curr Opin Chem Biol       Date:  2002-12       Impact factor: 8.822

3.  All-D-magainin: chirality, antimicrobial activity and proteolytic resistance.

Authors:  R Bessalle; A Kapitkovsky; A Gorea; I Shalit; M Fridkin
Journal:  FEBS Lett       Date:  1990-11-12       Impact factor: 4.124

4.  Ultrashort antibacterial and antifungal lipopeptides.

Authors:  Arik Makovitzki; Dorit Avrahami; Yechiel Shai
Journal:  Proc Natl Acad Sci U S A       Date:  2006-10-12       Impact factor: 11.205

5.  A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms.

Authors:  Marie Allesen-Holm; Kim Bundvig Barken; Liang Yang; Mikkel Klausen; Jeremy S Webb; Staffan Kjelleberg; Søren Molin; Michael Givskov; Tim Tolker-Nielsen
Journal:  Mol Microbiol       Date:  2006-02       Impact factor: 3.501

6.  Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement.

Authors:  Ian Chopra; Christopher Schofield; Martin Everett; Alex O'Neill; Keith Miller; Mark Wilcox; Jean-Marie Frère; Mike Dawson; Lloyd Czaplewski; Uros Urleb; Patrice Courvalin
Journal:  Lancet Infect Dis       Date:  2008-02       Impact factor: 25.071

7.  Extreme stability of helices formed by water-soluble poly-N-substituted glycines (polypeptoids) with alpha-chiral side chains.

Authors:  Tracy J Sanborn; Cindy W Wu; Ronald N Zuckermann; Annelise E Barron
Journal:  Biopolymers       Date:  2002-01       Impact factor: 2.505

Review 8.  Pulmonary infections in patients with cystic fibrosis.

Authors:  Sujatha Rajan; Lisa Saiman
Journal:  Semin Respir Infect       Date:  2002-03

9.  Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides.

Authors:  Nathaniel P Chongsiriwatana; James A Patch; Ann M Czyzewski; Michelle T Dohm; Andrey Ivankin; David Gidalevitz; Ronald N Zuckermann; Annelise E Barron
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-19       Impact factor: 11.205

10.  Biofilm formation by Stenotrophomonas maltophilia: modulation by quinolones, trimethoprim-sulfamethoxazole, and ceftazidime.

Authors:  Giovanni Di Bonaventura; Ilaria Spedicato; Domenico D'Antonio; Iole Robuffo; Raffaele Piccolomini
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191
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  40 in total

1.  Functional synergy between antimicrobial peptoids and peptides against Gram-negative bacteria.

Authors:  Nathaniel P Chongsiriwatana; Modi Wetzler; Annelise E Barron
Journal:  Antimicrob Agents Chemother       Date:  2011-08-22       Impact factor: 5.191

Review 2.  Will new generations of modified antimicrobial peptides improve their potential as pharmaceuticals?

Authors:  Nicole K Brogden; Kim A Brogden
Journal:  Int J Antimicrob Agents       Date:  2011-07-05       Impact factor: 5.283

3.  The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses.

Authors:  Shruti Padhee; Christina Smith; Haifan Wu; Yaqiong Li; Namitha Manoj; Qiao Qiao; Zoya Khan; Chuanhai Cao; Hang Yin; Jianfeng Cai
Journal:  Chembiochem       Date:  2014-03-21       Impact factor: 3.164

Review 4.  The development of antimicrobial γ-AApeptides.

Authors:  Fengyu She; Olapeju Oyesiku; Peiguang Zhou; Shiming Zhuang; David W Koenig; Jianfeng Cai
Journal:  Future Med Chem       Date:  2016-06-10       Impact factor: 3.808

5.  Rapid conversion of Pseudomonas aeruginosa to a spherical cell morphotype facilitates tolerance to carbapenems and penicillins but increases susceptibility to antimicrobial peptides.

Authors:  Leigh G Monahan; Lynne Turnbull; Sarah R Osvath; Debra Birch; Ian G Charles; Cynthia B Whitchurch
Journal:  Antimicrob Agents Chemother       Date:  2014-01-13       Impact factor: 5.191

6.  Rhesus θ-defensin-1 (RTD-1) exhibits in vitro and in vivo activity against cystic fibrosis strains of Pseudomonas aeruginosa.

Authors:  Paul M Beringer; Timothy J Bensman; Henry Ho; Melissa Agnello; Nicole Denovel; Albert Nguyen; Annie Wong-Beringer; Rosemary She; Dat Q Tran; Samuel M Moskowitz; Michael E Selsted
Journal:  J Antimicrob Chemother       Date:  2015-10-03       Impact factor: 5.790

Review 7.  Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

Authors:  Natalia Molchanova; Paul R Hansen; Henrik Franzyk
Journal:  Molecules       Date:  2017-08-29       Impact factor: 4.411

8.  Identification of peptides derived from the human antimicrobial peptide LL-37 active against biofilms formed by Pseudomonas aeruginosa using a library of truncated fragments.

Authors:  C Nagant; B Pitts; K Nazmi; M Vandenbranden; J G Bolscher; P S Stewart; J-P Dehaye
Journal:  Antimicrob Agents Chemother       Date:  2012-08-20       Impact factor: 5.191

Review 9.  Beyond conventional antibiotics - New directions for combination products to combat biofilm.

Authors:  Danir Fanisovich Bayramov; Jennifer Ann Neff
Journal:  Adv Drug Deliv Rev       Date:  2016-08-03       Impact factor: 15.470

10.  Peptoid Library Agar Diffusion (PLAD) Assay for the High-Throughput Identification of Antimicrobial Peptoids.

Authors:  Kevin J Fisher; Jeremy A Turkett; Ashley E Corson; Kevin L Bicker
Journal:  ACS Comb Sci       Date:  2016-05-26       Impact factor: 3.784
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