Literature DB >> 21416272

The triplet puzzle of homologies in receptor heteromers exists also in other types of protein-protein interactions.

Alexander O Tarakanov1, Kjell G Fuxe.   

Abstract

Based on our theory, we point out main triplets of amino acid residues in the GABAB1 receptor, found in the central and peripheral nervous system, which seem to be critical for both receptor heterodimerization and chemokine binding. The obtained results suggest that these triplets may "guide-and-clasp" protein-protein interactions playing a role, e.g., in neuroinflammation disorders.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21416272     DOI： 10.1007/s12031-011-9511-9

Source DB:  PubMed          Journal:  J Mol Neurosci        ISSN： 0895-8696            Impact factor:   3.444


  30 in total

Review 1.  Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons.

Authors:  Luigi F Agnati; Sergi Ferré; Carme Lluis; Rafael Franco; Kjell Fuxe
Journal:  Pharmacol Rev       Date:  2003-07-17       Impact factor: 25.468

2.  Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization.

Authors:  Dasiel O Borroto-Escuela; Manuel Narvaez; Daniel Marcellino; Concepción Parrado; José Angel Narvaez; Alexander O Tarakanov; Luigi F Agnati; Zaida Díaz-Cabiale; Kjell Fuxe
Journal:  Biochem Biophys Res Commun       Date:  2010-02-18       Impact factor: 3.575

Review 3.  Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function.

Authors:  Kjell Fuxe; Sergi Ferré; Meritxell Canals; Maria Torvinen; Anton Terasmaa; Daniel Marcellino; Steven R Goldberg; William Staines; Kirsten X Jacobsen; Carmen Lluis; Amina S Woods; Luigi F Agnati; Rafael Franco
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

Review 4.  Is the GABA B heterodimer a good drug target?

Authors:  Fiona H Marshall
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

Review 5.  The many roles of chemokines and chemokine receptors in inflammation.

Authors:  Israel F Charo; Richard M Ransohoff
Journal:  N Engl J Med       Date:  2006-02-09       Impact factor: 91.245

6.  Antifreeze protein from shorthorn sculpin: identification of the ice-binding surface.

Authors:  J Baardsnes; M Jelokhani-Niaraki; L H Kondejewski; M J Kuiper; C M Kay; R S Hodges; P L Davies
Journal:  Protein Sci       Date:  2001-12       Impact factor: 6.725

7.  Role of electrostatic interaction in receptor-receptor heteromerization.

Authors:  Amina S Woods; Francisco Ciruela; Kjell Fuxe; Luigi F Agnati; Carmen Lluis; Rafael Franco; Sergi Ferré
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

8.  Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.

Authors:  N Adya; L J Zhao; W Huang; I Boros; C Z Giam
Journal:  Proc Natl Acad Sci U S A       Date:  1994-06-07       Impact factor: 11.205

9.  The mighty arginine, the stable quaternary amines, the powerful aromatics, and the aggressive phosphate: their role in the noncovalent minuet.

Authors:  Amina S Woods
Journal:  J Proteome Res       Date:  2004 May-Jun       Impact factor: 4.466

Review 10.  International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.

Authors:  Jean-Philippe Pin; Richard Neubig; Michel Bouvier; Lakshmi Devi; Marta Filizola; Jonathan A Javitch; Martin J Lohse; Graeme Milligan; Krzysztof Palczewski; Marc Parmentier; Michael Spedding
Journal:  Pharmacol Rev       Date:  2007-03       Impact factor: 25.468
View more
  7 in total

1.  On the origin of the triplet puzzle of homologies in receptor heteromers: Toll-like receptor triplets in different types of receptors.

Authors:  Alexander O Tarakanov; Kjell G Fuxe; Dasiel O Borroto-Escuela
Journal:  J Neural Transm (Vienna)       Date:  2011-11-08       Impact factor: 3.575

2.  On the origin of the triplet puzzle of homologies in receptor heteromers: immunoglobulin triplets in different types of receptors.

Authors:  Alexander O Tarakanov; Kjell G Fuxe; Dasiel O Borroto-Escuela
Journal:  J Mol Neurosci       Date:  2011-09-20       Impact factor: 3.444

3.  Integrin triplets of marine sponges in human brain receptor heteromers.

Authors:  Alexander O Tarakanov; Kjell G Fuxe; Dasiel O Borroto-Escuela
Journal:  J Mol Neurosci       Date:  2012-05-10       Impact factor: 3.444

Review 4.  Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field.

Authors:  Kjell Fuxe; Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Miklós Palkovits; Alexander O Tarakanov; Francisco Ciruela; Luigi F Agnati
Journal:  Neuropsychopharmacology       Date:  2013-09-06       Impact factor: 7.853

5.  Design, synthesis and biological evaluation of bivalent ligands against A(1)-D(1) receptor heteromers.

Authors:  Jian Shen; Lei Zhang; Wan-ling Song; Tao Meng; Xin Wang; Lin Chen; Lin-yin Feng; Ye-chun Xu; Jing-kang Shen
Journal:  Acta Pharmacol Sin       Date:  2013-01-21       Impact factor: 6.150

6.  Integrin triplets of marine sponges in the murine and human MHCI-CD8 interface and in the interface of human neural receptor heteromers and subunits.

Authors:  Alexander O Tarakanov; Kjell G Fuxe
Journal:  Springerplus       Date:  2013-03-22

7.  The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components.

Authors:  Dasiel O Borroto-Escuela; Ismel Brito; Wilber Romero-Fernandez; Michael Di Palma; Julia Oflijan; Kamila Skieterska; Jolien Duchou; Kathleen Van Craenenbroeck; Diana Suárez-Boomgaard; Alicia Rivera; Diego Guidolin; Luigi F Agnati; Kjell Fuxe
Journal:  Int J Mol Sci       Date:  2014-05-14       Impact factor: 5.923
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.