Literature DB >> 21932037

On the origin of the triplet puzzle of homologies in receptor heteromers: immunoglobulin triplets in different types of receptors.

Alexander O Tarakanov1, Kjell G Fuxe, Dasiel O Borroto-Escuela.   

Abstract

Based on our theory, we have discovered main triplets of amino acid residues in the GABAB1 receptor and several other neural receptors which seem to come from immunoglobulin chains and appear also as homologies in receptor heteromers. The obtained results strengthen our hypothesis that these triplets may "guide-and-clasp" receptor-receptor interactions playing a role, e.g., in neuroinflammation disorders.

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Year:  2011        PMID： 21932037     DOI： 10.1007/s12031-011-9649-5

Source DB:  PubMed          Journal:  J Mol Neurosci        ISSN： 0895-8696            Impact factor:   3.444


  15 in total

1.  Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells.

Authors:  Shunji Suzuki; Linda F Chuang; Peter Yau; Roy H Doi; Ronald Y Chuang
Journal:  Exp Cell Res       Date:  2002-11-01       Impact factor: 3.905

2.  Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers.

Authors:  M Rocheville; D C Lange; U Kumar; R Sasi; R C Patel; Y C Patel
Journal:  J Biol Chem       Date:  2000-03-17       Impact factor: 5.157

Review 3.  Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity.

Authors:  Alice Guyon; Jean-Louis Nahon
Journal:  J Mol Endocrinol       Date:  2007-03       Impact factor: 5.098

4.  Heterodimerization of FGF-receptor 1 and PDGF-receptor-alpha: a novel mechanism underlying the inhibitory effect of PDGF-BB on FGF-2 in human cells.

Authors:  Debora Faraone; Maria S Aguzzi; Gianluca Ragone; Katia Russo; Maurizio C Capogrossi; Antonio Facchiano
Journal:  Blood       Date:  2005-12-01       Impact factor: 22.113

5.  Possible role of receptor heteromers in multiple sclerosis.

Authors:  A O Tarakanov; K G Fuxe; L F Agnati; L B Goncharova
Journal:  J Neural Transm (Vienna)       Date:  2009-02-20       Impact factor: 3.575

Review 6.  Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration.

Authors:  Dasiel O Borroto-Escuela; Alexander O Tarakanov; Diego Guidolin; Francisco Ciruela; Luigi F Agnati; Kjell Fuxe
Journal:  IUBMB Life       Date:  2011-07       Impact factor: 3.885

7.  Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family.

Authors:  Wilber Romero-Fernandez; Dasiel O Borroto-Escuela; Alexander O Tarakanov; Giuseppa Mudó; Manuel Narvaez; Mileidys Pérez-Alea; Luigi F Agnati; Francisco Ciruela; Natale Belluardo; Kjell Fuxe
Journal:  Biochem Biophys Res Commun       Date:  2011-05-20       Impact factor: 3.575

8.  GABA(B) receptor activation enhances mGluR-mediated responses at cerebellar excitatory synapses.

Authors:  M Hirono; T Yoshioka; S Konishi
Journal:  Nat Neurosci       Date:  2001-12       Impact factor: 24.884

Review 9.  Cell adhesion receptors and nuclear receptors are highly conserved from the lowest metazoa (marine sponges) to vertebrates.

Authors:  V Gamulin; B Rinkevich; H Schäcke; M Kruse; I M Müller; W E Müller
Journal:  Biol Chem Hoppe Seyler       Date:  1994-09

10.  Interferon-gamma directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-gamma receptor and AMPA GluR1 receptor.

Authors:  Tetsuya Mizuno; Guiqin Zhang; Hideyuki Takeuchi; Jun Kawanokuchi; Jinyan Wang; Yoshifumi Sonobe; Shijie Jin; Naoki Takada; Yukio Komatsu; Akio Suzumura
Journal:  FASEB J       Date:  2008-01-15       Impact factor: 5.191
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  9 in total

1.  Integrin triplets of marine sponges in human brain receptor heteromers.

Authors:  Alexander O Tarakanov; Kjell G Fuxe; Dasiel O Borroto-Escuela
Journal:  J Mol Neurosci       Date:  2012-05-10       Impact factor: 3.444

Review 2.  Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field.

Authors:  Kjell Fuxe; Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Miklós Palkovits; Alexander O Tarakanov; Francisco Ciruela; Luigi F Agnati
Journal:  Neuropsychopharmacology       Date:  2013-09-06       Impact factor: 7.853

Review 3.  The role of transmitter diffusion and flow versus extracellular vesicles in volume transmission in the brain neural-glial networks.

Authors:  Dasiel O Borroto-Escuela; Luigi F Agnati; Karl Bechter; Anders Jansson; Alexander O Tarakanov; Kjell Fuxe
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-07-05       Impact factor: 6.237

4.  On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation.

Authors:  Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Alicia Rivera; Kathleen Van Craenenbroeck; Alexander O Tarakanov; Luigi F Agnati; Kjell Fuxe
Journal:  Evid Based Complement Alternat Med       Date:  2013-07-17       Impact factor: 2.629

Review 5.  Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson's disease and its treatment.

Authors:  Dasiel O Borroto-Escuela; Kjell Fuxe
Journal:  J Neural Transm (Vienna)       Date:  2019-01-14       Impact factor: 3.575

6.  Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS.

Authors:  Dasiel O Borroto-Escuela; Kjell Fuxe
Journal:  Front Mol Neurosci       Date:  2019-09-25       Impact factor: 5.639

7.  Integrin triplets of marine sponges in the murine and human MHCI-CD8 interface and in the interface of human neural receptor heteromers and subunits.

Authors:  Alexander O Tarakanov; Kjell G Fuxe
Journal:  Springerplus       Date:  2013-03-22

8.  The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components.

Authors:  Dasiel O Borroto-Escuela; Ismel Brito; Wilber Romero-Fernandez; Michael Di Palma; Julia Oflijan; Kamila Skieterska; Jolien Duchou; Kathleen Van Craenenbroeck; Diana Suárez-Boomgaard; Alicia Rivera; Diego Guidolin; Luigi F Agnati; Kjell Fuxe
Journal:  Int J Mol Sci       Date:  2014-05-14       Impact factor: 5.923

Review 9.  Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors.

Authors:  Dasiel O Borroto-Escuela; Miguel Perez De La Mora; Paul Manger; Manuel Narváez; Sarah Beggiato; Minerva Crespo-Ramírez; Gemma Navarro; Karolina Wydra; Zaida Díaz-Cabiale; Alicia Rivera; Luca Ferraro; Sergio Tanganelli; Małgorzata Filip; Rafael Franco; Kjell Fuxe
Journal:  Front Synaptic Neurosci       Date:  2018-07-10
  9 in total

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