Literature DB >> 21411780

Common genomic aberrations in basaloid squamous cell carcinoma and carcinosarcoma of the esophagus detected by CGH and array CGH.

Inga-Marie Schaefer1, Christina Enders, Andreas Polten, Florian Haller, Andreas M J Frölich, Silke Cameron, Philipp Schüler, Peter Schweiger, Bastian Gunawan, Alexander Beham, László Füzesi.   

Abstract

Basaloid squamous cell carcinoma (BSCC) and carcinosarcoma of the esophagus are rare entities, making up fewer than 2% of esophageal malignancies. Comparative genomic hybridization (CGH) in 1 case of BSCC and 2 cases of carcinosarcoma and subsequent array CGH in 1 case each of BSCC and carcinosarcoma revealed common chromosomal gains at 2p25.3-2p12, 7q21.3-7q22.3, and 11q13.2-11q13.4. Chromosomal losses at 13q31qter were observed in both carcinosarcomas. In addition, progression of genomic instability from in situ to invasive carcinosarcoma could be demonstrated by using array CGH. Our observations suggest a common genetic origin of BSCC and carcinosarcoma.

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Year:  2011        PMID： 21411780     DOI： 10.1309/AJCPZ1O7UUUISPNR

Source DB:  PubMed          Journal:  Am J Clin Pathol        ISSN： 0002-9173            Impact factor:   2.493


  9 in total

1.  A case of long-term survival after pulmonary resection for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the esophagus.

Authors:  Masashi Takemura; Kayo Yoshida; Yushi Fujiwara; Katsunobu Sakurai; Mamiko Takii
Journal:  Int J Surg Case Rep       Date:  2012-06-01

2.  Basaloid squamous cell carcinoma of the esophagus.

Authors:  Shao-Bin Chen; Hong-Rui Weng; Geng Wang; Jie-Sheng Yang; Wei-Ping Yang; Hua Li; Di-Tian Liu; Yu-Ping Chen
Journal:  J Cancer Res Clin Oncol       Date:  2012-03-15       Impact factor: 4.553

3.  Array CGH analysis of the rare laryngeal basaloid squamous cell carcinoma: a case report.

Authors:  Szilvia Ecsedi; László Tóth; Margit Balázs
Journal:  Int J Clin Exp Pathol       Date:  2012-10-01

4.  Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma.

Authors:  Dessy Chan; Miriam Yuen-Tung Tsoi; Christina Di Liu; Sau-Hing Chan; Simon Ying-Kit Law; Kwok-Wah Chan; Yuen-Piu Chan; Vinod Gopalan; Alfred King-Yin Lam; Johnny Cheuk-On Tang
Journal:  World J Gastroenterol       Date:  2013-05-14       Impact factor: 5.742

5.  Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing.

Authors:  Alberto Paniz-Mondolfi; Rajesh Singh; George Jour; Mandana Mahmoodi; A Hafeez Diwan; Bedia A Barkoh; Ronald Cason; Yve Huttenbach; Gustavo Benaim; John Galbincea; Rajyalakshmi Luthra
Journal:  Virchows Arch       Date:  2014-07-17       Impact factor: 4.064

6.  Neuroendocrine carcinoma in a mediastinal teratoma as a rare variant of somatic-type malignancy.

Authors:  Inga-Marie Schaefer; Patrick Zardo; Stefan Freermann; Alexander Marx; Philipp Ströbel; Stefan Fischer
Journal:  Virchows Arch       Date:  2013-08-25       Impact factor: 4.064

7.  Clinical and genetic characterization of basal cell carcinoma and breast cancer in a single patient.

Authors:  Alessandra Morelle; Rodrigo Cericatto; Ana Cristina Victorino Krepischi; Itamar Romano Garcia Ruiz
Journal:  Springerplus       Date:  2014-08-22

8.  Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus.

Authors:  Hirotaka Ishida; Toru Nakano; Fumiyoshi Fujishima; Takashi Kamei; Yusuke Taniyama; Tadashi Sakurai; Chiaki Sato; Toshiaki Fukutomi; Kuroudo Kamiya; Yohei Ozawa; Hironobu Sasano; Noriaki Ohuchi
Journal:  Int J Surg Case Rep       Date:  2015-11-26

Review 9.  Blastomatoid pulmonary carcinosarcoma: report of a case with a review of the literature.

Authors:  Inga-Marie Schaefer; Carsten-Oliver Sahlmann; Tobias Overbeck; Stefan Schweyer; Jan Menke
Journal:  BMC Cancer       Date:  2012-09-25       Impact factor: 4.430
  9 in total

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