Literature DB >> 21404376

Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis.

Alexander Lang1, Stefan Polnick, Tristan Nicke, Peter William, Eugenio P Patallo, James H Naismith, Karl-Heinz van Pée.   

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Year:  2011        PMID： 21404376     DOI： 10.1002/anie.201007896

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  21 in total

1.  Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids.

Authors:  Amy E Fraley; Marc Garcia-Borràs; Ashootosh Tripathi; Dheeraj Khare; Eduardo V Mercado-Marin; Hong Tran; Qingyun Dan; Gabrielle P Webb; Katharine R Watts; Phillip Crews; Richmond Sarpong; Robert M Williams; Janet L Smith; K N Houk; David H Sherman
Journal:  J Am Chem Soc       Date:  2017-08-21       Impact factor: 15.419

Review 2.  Halogenase engineering and its utility in medicinal chemistry.

Authors:  Amy E Fraley; David H Sherman
Journal:  Bioorg Med Chem Lett       Date:  2018-04-30       Impact factor: 2.823

3.  Accelerating the semisynthesis of alkaloid-based drugs through metabolic engineering.

Authors:  Amy M Ehrenworth; Pamela Peralta-Yahya
Journal:  Nat Chem Biol       Date:  2017-02-15       Impact factor: 15.040

4.  Improving the stability and catalyst lifetime of the halogenase RebH by directed evolution.

Authors:  Catherine B Poor; Mary C Andorfer; Jared C Lewis
Journal:  Chembiochem       Date:  2014-05-21       Impact factor: 3.164

5.  Enantioselective Desymmetrization of Methylenedianilines via Enzyme-Catalyzed Remote Halogenation.

Authors:  James T Payne; Paul H Butkovich; Yifan Gu; Kyle N Kunze; Hyun June Park; Duo-Sheng Wang; Jared C Lewis
Journal:  J Am Chem Soc       Date:  2018-01-08       Impact factor: 15.419

6.  Structure-based switch of regioselectivity in the flavin-dependent tryptophan 6-halogenase Thal.

Authors:  Ann-Christin Moritzer; Hannah Minges; Tina Prior; Marcel Frese; Norbert Sewald; Hartmut H Niemann
Journal:  J Biol Chem       Date:  2018-12-17       Impact factor: 5.157

Review 7.  Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.

Authors:  Vinayak Agarwal; Zachary D Miles; Jaclyn M Winter; Alessandra S Eustáquio; Abrahim A El Gamal; Bradley S Moore
Journal:  Chem Rev       Date:  2017-01-20       Impact factor: 60.622

8.  Regioselective arene halogenation using the FAD-dependent halogenase RebH.

Authors:  James T Payne; Mary C Andorfer; Jared C Lewis
Journal:  Angew Chem Int Ed Engl       Date:  2013-04-16       Impact factor: 15.336

Review 9.  Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis.

Authors:  Mary C Andorfer; Jared C Lewis
Journal:  Annu Rev Biochem       Date:  2018-03-28       Impact factor: 23.643

10.  Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.

Authors:  Abrahim El Gamal; Vinayak Agarwal; Stefan Diethelm; Imran Rahman; Michelle A Schorn; Jennifer M Sneed; Gordon V Louie; Kristen E Whalen; Tracy J Mincer; Joseph P Noel; Valerie J Paul; Bradley S Moore
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-21       Impact factor: 11.205
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