Literature DB >> 21402354

Profaning the ultimate sanctuary: HIV latency in hematopoietic stem cells.

Didier Trono1, Flavia Marzetta2.   

Abstract

The early establishment of a reservoir of latently infected T cells is a sobering obstacle to HIV eradication, in spite of the efficacy of current antiretroviral therapies. That latent proviruses might also hide in multipotent hematopoietic stem cells suggests an even more formidable challenge and potentially has therapeutic implications.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID: 21402354     DOI: 10.1016/j.chom.2011.03.001

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  3 in total

Review 1.  Eliminating the HIV reservoir.

Authors:  Alain Lafeuillade
Journal:  Curr HIV/AIDS Rep       Date:  2012-06       Impact factor: 5.071

Review 2.  Achieving a cure for HIV infection: do we have reasons to be optimistic?

Authors:  Valentin Le Douce; Andrea Janossy; Houda Hallay; Sultan Ali; Raphael Riclet; Olivier Rohr; Christian Schwartz
Journal:  J Antimicrob Chemother       Date:  2012-02-01       Impact factor: 5.790

Review 3.  Review of Current Cell-Penetrating Antibody Developments for HIV-1 Therapy.

Authors:  Muhamad Alif Che Nordin; Sin-Yeang Teow
Journal:  Molecules       Date:  2018-02-06       Impact factor: 4.411

  3 in total

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