Literature DB >> 2140234

Effect of salmon calcitonin on the infiltration of T lymphocytes in a synovium-like membrane of a rat inflammatory model.

A Grieder1, M Felder, W Schaffner.   

Abstract

The effect of salmon calcitonin (SCT) on the number of T lymphocytes accumulating in air pouch lining membranes produced on the back of Wistar rats was studied. SCT was given from day 0 through day seven following the air cavitation by daily injections of 2.5-20 micrograms/kg directly into the air cavity. Compared with saline controls, treatment with SCT caused a clear reduction in percentage of T lymphocytes, T helper cells and T non-helper subset in the synovial-like air pouch lining as revealed by FITC-labeled monoclonal antibodies and quantified by flow cytophotometric measurements. This effect may be due to a reduction in local vascular permeability caused by SCT.

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Year:  1990        PMID： 2140234     DOI： 10.1007/bf01966462

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  24 in total

1.  Surface characteristics of synovial fluid and peripheral blood lymphocytes in inflammatory arthritis.

Authors:  A I Brenner; M A Scheinberg; E S Cathcart
Journal:  Arthritis Rheum       Date:  1975 Jul-Aug

2.  On the mechanism through which hydrocortisone affects the resistance of tissues to injury; an experimental study with the granuloma pouch technique.

Authors:  H SELYE
Journal:  J Am Med Assoc       Date:  1953-07-25

3.  Predominantly T-cell infiltrate in rheumatoid synovial membranes.

Authors:  J A Van Boxel; S A Paget
Journal:  N Engl J Med       Date:  1975-09-11       Impact factor: 91.245

4.  Intercellular cement and capillary permeability.

Authors:  R CHAMBERS; B W ZWEIFACH
Journal:  Physiol Rev       Date:  1947-07       Impact factor: 37.312

5.  Lymphocytes eluted from synovial tissue of juvenile rheumatoid arthritis patients.

Authors:  T G Abrahamsen; S S Frøoland; J B Natvig; J Pahle
Journal:  Arthritis Rheum       Date:  1977-04

6.  In vitro effects of calcitonin on inflammation.

Authors:  S Havelka; J Hurych
Journal:  Horm Metab Res       Date:  1980-05       Impact factor: 2.936

7.  Antigen and unspecific mitogen stimulation of lymphocytes eluted from rheumatoid inflammatory tissue.

Authors:  T G Abrahamsen; S S Fróland; J B Natvig; J Pahle
Journal:  Scand J Immunol       Date:  1976       Impact factor: 3.487

8.  Inhibition of mitogen-stimulated T lymphocyte proliferation by calcitonin gene-related peptide.

Authors:  Y Umeda; M Takamiya; H Yoshizaki; M Arisawa
Journal:  Biochem Biophys Res Commun       Date:  1988-07-15       Impact factor: 3.575

9.  Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products.

Authors:  S G Amara; V Jonas; M G Rosenfeld; E S Ong; R M Evans
Journal:  Nature       Date:  1982-07-15       Impact factor: 49.962

10.  Cell-mediated immunity in rheumatic diseases. II. Mitogen responses in RA, SLE, and other illnesses: correlation with T- and B-lymphocyte populations.

Authors:  M D Lockshin; A C Eisenhauer; R Kohn; M Weksler; S Block; S B Mushlin
Journal:  Arthritis Rheum       Date:  1975 May-Jun
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  2 in total

Review 1.  Calcitonin and its antinociceptive activity: animal and human investigations 1975-1992.

Authors:  P C Braga
Journal:  Agents Actions       Date:  1994-05

2.  The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis.

Authors:  Adam Al-Kashi; Trinidad Montero-Melendez; Niloufar Moradi-Bidhendi; James P Gilligan; Nozer Mehta; Mauro Perretti
Journal:  PLoS One       Date:  2013-02-05       Impact factor: 3.240
  2 in total

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