Young Cheol Yoo1, Ki Ho Park. 1. Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. demian7435@gmail.com
Abstract
PURPOSE: To investigate the influence of angular width and peripapillary position of localized retinal nerve fiber layer (RNFL) defects on their detection by the time-domain optical coherence tomography (OCT). METHODS: Fast RNFL Stratus OCT scans were obtained from 186 eyes of 186 newly detected glaucoma patients with only a single, localized RNFL defect in either eye. The RNFL defects were divided into subgroups according to their angular width at 15° intervals and superior or inferior position. In the sector average graph of OCT results, abnormal clock-hour sectors were evaluated at P < 5%. RESULTS: Among 154 eyes included in the final data analysis, mean angular width of localized RNFL defects was 21.82 ± 10.38°, and 108 eyes (70.1%) had an inferiorly located RNFL defect. Localized RNFL defects with an angular width interval of 30° to 45° were more frequently detected by Stratus OCT than those with an angular width of <15° (odds ratio = 30.32, P = 0.001). Inferior RNFL defects were not detected more frequently by Stratus OCT than superior RNFL defects (odds ratio = 1.58, P = 0.24). CONCLUSIONS: Only the angular width of localized RNFL defects had a significant influence on the sensitivity of the time-domain OCT.
PURPOSE: To investigate the influence of angular width and peripapillary position of localized retinal nerve fiber layer (RNFL) defects on their detection by the time-domain optical coherence tomography (OCT). METHODS: Fast RNFL Stratus OCT scans were obtained from 186 eyes of 186 newly detected glaucomapatients with only a single, localized RNFL defect in either eye. The RNFL defects were divided into subgroups according to their angular width at 15° intervals and superior or inferior position. In the sector average graph of OCT results, abnormal clock-hour sectors were evaluated at P < 5%. RESULTS: Among 154 eyes included in the final data analysis, mean angular width of localized RNFL defects was 21.82 ± 10.38°, and 108 eyes (70.1%) had an inferiorly located RNFL defect. Localized RNFL defects with an angular width interval of 30° to 45° were more frequently detected by Stratus OCT than those with an angular width of <15° (odds ratio = 30.32, P = 0.001). Inferior RNFL defects were not detected more frequently by Stratus OCT than superior RNFL defects (odds ratio = 1.58, P = 0.24). CONCLUSIONS: Only the angular width of localized RNFL defects had a significant influence on the sensitivity of the time-domain OCT.
Authors: J S Schuman; M R Hee; C A Puliafito; C Wong; T Pedut-Kloizman; C P Lin; E Hertzmark; J A Izatt; E A Swanson; J G Fujimoto Journal: Arch Ophthalmol Date: 1995-05
Authors: Mohamed A E Soliman; Thomas J T P Van Den Berg; Al-Araby A Ismaeil; Leo A M S De Jong; Marc D De Smet Journal: Am J Ophthalmol Date: 2002-02 Impact factor: 5.258