Laurent Excoffier1, Matthieu Foll. 1. Institute of Ecology and Evolution, University of Berne, Berne, Switzerland. laurent.excoffier@iee.unibe.ch
Abstract
MOTIVATION: Genetic studies focus on increasingly larger genomic regions of both extant and ancient DNA, and there is a need for simulation software to match these technological advances. We present here a new coalescent-based simulation program fastsimcoal, which is able to quickly simulate a variety of genetic markers scattered over very long genomic regions with arbitrary recombination patterns under complex evolutionary scenarios. AVAILABILITY AND IMPLEMENTATION: fastsimcoal is a C++ program compiled for Windows, MacOsX and Linux platforms. It is freely available at cmpg.unibe.ch/software/fastsimcoal/, together with its detailed user manual and example input files.
MOTIVATION: Genetic studies focus on increasingly larger genomic regions of both extant and ancient DNA, and there is a need for simulation software to match these technological advances. We present here a new coalescent-based simulation program fastsimcoal, which is able to quickly simulate a variety of genetic markers scattered over very long genomic regions with arbitrary recombination patterns under complex evolutionary scenarios. AVAILABILITY AND IMPLEMENTATION: fastsimcoal is a C++ program compiled for Windows, MacOsX and Linux platforms. It is freely available at cmpg.unibe.ch/software/fastsimcoal/, together with its detailed user manual and example input files.
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Authors: E L Carroll; R Alderman; J L Bannister; M Bérubé; P B Best; L Boren; C S Baker; R Constantine; K Findlay; R Harcourt; L Lemaire; P J Palsbøll; N J Patenaude; V J Rowntree; J Seger; D Steel; L O Valenzuela; M Watson; O E Gaggiotti Journal: Heredity (Edinb) Date: 2018-05-03 Impact factor: 3.821