| Literature DB >> 21381678 |
Xiaoping Peng1, Yi Wang, Kunlai Sun, Peipei Liu, Xia Yin, Weiming Zhu.
Abstract
Five new cerebrosides, chrysogesides A-E (1-5), and two new 2-pyridone alkaloids, chrysogedones A and B (6 and 7), were isolated from the fermentation broth of Penicillium chrysogenum PXP-55, a halotolerant fungus grown in a hypersaline medium. Among them, chrysogesides B-D (2-4) are the first cerebrosides that contain an unsaturated C(19)-fatty acid. Their structures were identified by spectroscopic and chemical methods, including CD spectroscopy as well as the modified Mosher's method. Compound 2 showed antimicrobial activity against Enterobacter aerogenes with an MIC value of 1.72 μM.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21381678 DOI： 10.1021/np1008976
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050