Chuan Li1, Kai Mi, Tian-fu Wen, Lu-nan Yan, Bo Li. 1. Division of Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, China.
Abstract
BACKGROUND: Hepatectomy is one of the primary methods used in the treatment of hepatic lesions and liver graft harvesting. However, few studies have evaluated the postoperative recovery process of donor patients and that of normal liver hepatic patients following a right hepatectomy procedure. METHODS: For this current study, the clinical data from the most recent 60 cases of each patient type receiving treatment at West China Hospital (group A [donors] and group B [normal liver hepatic patients]) were retrospectively analysed. Preoperative parameters, intraoperative variables, postoperative complications classified by the Clavien-Dindo classification system, and liver function changes were all statistically analysed and compared. RESULTS: The preoperative parameters of the two groups were comparable. Group A experienced more intraoperative bleeding; however, the average amount of blood transfusion products was similar between the two groups. The overall postoperative surgical morbidity incidence for group A was 31.7% and for group B was 35%, with a p value of 0.699. The total bilirubin level and coagulation functions of group A were worse than what was observed in group B during the early postoperative period. CONCLUSION: Live liver donation via right hepatectomy results in similar complication rates and average blood product use to non-cirrhotic hepatic diseases. However, following the procedure, donor liver function showed greater dysfunction during the early postoperative period.
BACKGROUND: Hepatectomy is one of the primary methods used in the treatment of hepatic lesions and liver graft harvesting. However, few studies have evaluated the postoperative recovery process of donorpatients and that of normal liver hepaticpatients following a right hepatectomy procedure. METHODS: For this current study, the clinical data from the most recent 60 cases of each patient type receiving treatment at West China Hospital (group A [donors] and group B [normal liver hepaticpatients]) were retrospectively analysed. Preoperative parameters, intraoperative variables, postoperative complications classified by the Clavien-Dindo classification system, and liver function changes were all statistically analysed and compared. RESULTS: The preoperative parameters of the two groups were comparable. Group A experienced more intraoperative bleeding; however, the average amount of blood transfusion products was similar between the two groups. The overall postoperative surgical morbidity incidence for group A was 31.7% and for group B was 35%, with a p value of 0.699. The total bilirubin level and coagulation functions of group A were worse than what was observed in group B during the early postoperative period. CONCLUSION: Live liver donation via right hepatectomy results in similar complication rates and average blood product use to non-cirrhotic hepatic diseases. However, following the procedure, donor liver function showed greater dysfunction during the early postoperative period.
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