Literature DB >> 2137853

Presence of clonal T cell populations in chronic B lymphocytic leukemia and smoldering myeloma.

T Wen1, H Mellstedt, M Jondal.   

Abstract

Clonality in the non-neoplastic T cell population was investigated in 21 patients with B cell chronic leukemic (B-CLL) or multiple myeloma (MM) by probing for TCR beta chain gene rearrangements using Southern blot analysis. In three patients with a benign form of B-CLL (stage 0), and in one patient with smoldering MM, evidence was found for predominant T cell clones. As cellular immunity against the malignant cells may be important in leukemia, the results are discussed in view of the potential role of T cell immunity in B-CLL and MM.

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Year:  1990        PMID： 2137853      PMCID： PMC2187776          DOI： 10.1084/jem.171.3.659

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  31 in total

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Journal:  Blood       Date:  1975-08       Impact factor: 22.113

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Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

Review 3.  Melanoma antigens: immunological and biological characterization and clinical significance.

Authors:  M Herlyn; H Koprowski
Journal:  Annu Rev Immunol       Date:  1988       Impact factor: 28.527

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Authors:  S M Fu; R J Winchester; H G Kunkel
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

5.  Monoclonal lymphocyte population in human plasma cell myeloma.

Authors:  H Mellstedt; S Hammarström; G Holm
Journal:  Clin Exp Immunol       Date:  1974-07       Impact factor: 4.330

6.  S-phase lymphocytes in chronic lymphocytic leukemia (CLL) in relation to immunoglobulin isotypes on the leukemic clone and to disease activity.

Authors:  E Kimby; H Mellstedt; B Nilsson; B Tribukait; M Björkholm; G Holm
Journal:  Leukemia       Date:  1987-05       Impact factor: 11.528

7.  Expression of myelomonocytic antigens on chronic lymphocytic leukemia B cells correlates with their ability to produce interleukin 1.

Authors:  F Morabito; E F Prasthofer; N E Dunlap; C E Grossi; A B Tilden
Journal:  Blood       Date:  1987-12       Impact factor: 22.113

8.  Low IL-1 beta production in leukemic cells from progressive B cell chronic leukemia (B-CLL).

Authors:  M Aguilar-Santelises; J F Amador; H Mellstedt; M Jondal
Journal:  Leuk Res       Date:  1989       Impact factor: 3.156

9.  Clonal rearrangement of the beta-T cell receptor gene in multiple myeloma.

Authors:  J Berenson; A Lichtenstein
Journal:  Leukemia       Date:  1989-02       Impact factor: 11.528

10.  Myeloma proteins as tumor-specific transplantation antigens.

Authors:  R G Lynch; R J Graff; S Sirisinha; E S Simms; H N Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205
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  10 in total

1.  Expansion of CD4+ T cells with a cytotoxic phenotype in patients with B-chronic lymphocytic leukaemia (B-CLL).

Authors:  N Porakishvili; T Roschupkina; T Kalber; A P Jewell; K Patterson; K Yong; P M Lydyard
Journal:  Clin Exp Immunol       Date:  2001-10       Impact factor: 4.330

2.  Tumour infiltrating T-cells in gastric lymphoma.

Authors:  T Hussell; P G Isaacson; J Spencer
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

3.  T cell heterogeneity in patients with common variable immunodeficiency as assessed by abnormalities of T cell subpopulations and T cell receptor gene analysis.

Authors:  F Pandolfi; L Trentin; J E San Martin; J T Wong; J T Kurnick; R A Moscicki
Journal:  Clin Exp Immunol       Date:  1992-08       Impact factor: 4.330

4.  Oligoclonal T cell receptor gene rearrangements in blood lymphocytes of patients with acute Epstein-Barr virus-induced infectious mononucleosis.

Authors:  J G Strickler; L A Movahed; K J Gajl-Peczalska; C A Horwitz; R D Brunning; L M Weiss
Journal:  J Clin Invest       Date:  1990-10       Impact factor: 14.808

Review 5.  Immunologic monitoring in chronic lymphocytic leukemia.

Authors:  William G Wierda
Journal:  Curr Oncol Rep       Date:  2003-09       Impact factor: 5.075

6.  Generation of T cell clones binding F(ab')2 fragments of the idiotypic immunoglobulin in patients with monoclonal gammopathy.

Authors:  A Osterborg; M Masucci; S Bergenbrant; G Holm; A K Lefvert; H Mellstedt
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

7.  The human T cell antigen receptor repertoire: skewed use of V beta gene families by CD8+ T cells.

Authors:  G R Clarke; C A Humphrey; F C Lancaster; A W Boylston
Journal:  Clin Exp Immunol       Date:  1994-05       Impact factor: 4.330

Review 8.  T Cells in Chronic Lymphocytic Leukemia: A Two-Edged Sword.

Authors:  Elisavet Vlachonikola; Kostas Stamatopoulos; Anastasia Chatzidimitriou
Journal:  Front Immunol       Date:  2021-01-20       Impact factor: 7.561

9.  Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia.

Authors:  Tom A Mulder; Lucía Peña-Pérez; Anna Berglöf; Stephan Meinke; H Yesid Estupiñán; Kia Heimersson; Rula Zain; Robert Månsson; C I Edvard Smith; Marzia Palma
Journal:  Hemasphere       Date:  2021-04-26

Review 10.  Harnessing the Effects of BTKi on T Cells for Effective Immunotherapy against CLL.

Authors:  Maissa Mhibik; Adrian Wiestner; Clare Sun
Journal:  Int J Mol Sci       Date:  2019-12-20       Impact factor: 5.923
  10 in total

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