Literature DB >> 803528

Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes.

S M Fu, R J Winchester, H G Kunkel.   

Abstract

Certain cases of chronic lymphocytic leukemia possess monoclonal bands in the serum. Idiotypic antibodies to the isolated IgM protein of one such case demonstrated that the leukemic lymphocytes carried the identical specificity on their lymphocytes. Both the lymphocyte IgM and the IgD possessed this same specificity. This was demonstrated best through the use of rhodamine-conjugated Fab fragments of IgM- and IgD-specific antisera which were both capped by the idiotypic antiserum.

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Year:  1975        PMID： 803528

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  42 in total

1.  Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen.

Authors:  Bao Hoa Duong; Takayuki Ota; Djemel Aït-Azzouzene; Miyo Aoki-Ota; José Luis Vela; Christoph Huber; Kevin Walsh; Amanda L Gavin; David Nemazee
Journal:  J Immunol       Date:  2010-03-15       Impact factor: 5.422

Review 2.  Immune deficiencies in chronic lymphocytic leukemia and multiple myeloma.

Authors:  A Winkelstein; P S Jordan
Journal:  Clin Rev Allergy       Date:  1992 Spring-Summer

3.  Blocking of primary in vitro antibody responses to thymus-independent and thymus-dependent antigens with antiserum specific for IgM or IgD.

Authors:  J C Cambier; F S Ligler; J W Uhr; J R Kettman; E S Vitetta
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

4.  Evidence for monoclonal proliferation in prolymphocytic leukemia of T-cell orgin. A cytogenetic and Quantitative immunoautoradiographic analysis.

Authors:  E Thiel; M Bauchinger; H Rodt; D Huhn; H Theml; S Thierfelder
Journal:  Blut       Date:  1977-12

Review 5.  Malignant lymphomas--a conceptual understanding of morphologic diversity. A review.

Authors:  R B Mann; E S Jaffe; C W Berard
Journal:  Am J Pathol       Date:  1979-01       Impact factor: 4.307

6.  The natural antibody response to E. coli includes antibodies of the IgD class.

Authors:  H F Sewell; L Chambers; V Maxwell; J B Matthews; R Jefferis
Journal:  Clin Exp Immunol       Date:  1978-01       Impact factor: 4.330

7.  Lymphocyte surface IgD and IgM in Macaca monkeys: ontogeny, tissue distribution and occurrence on individual lymphocytes.

Authors:  L N Martin; G A Leslie
Journal:  Immunology       Date:  1977-12       Impact factor: 7.397

Review 8.  The polyclonal expression of immunoglobulin variable region determinants on the membrane of B cells and their precursors.

Authors:  A Coutinho; L Forni; R R Bernabé
Journal:  Springer Semin Immunopathol       Date:  1980-08

9.  Cell surface markers in chronic lymphatic leukaemia.

Authors: 
Journal:  Br Med J       Date:  1979-10-13

10.  Chronic lymphocytic leukemia cells lack the 185,000-dalton macromolecular insoluble cold globulin present on normal B lymphocytes.

Authors:  M A Simmonds; G Sobczak; S P Hauptman
Journal:  J Clin Invest       Date:  1981-03       Impact factor: 14.808
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