Behpour Yousefi1, Azam Azargon. 1. Department of Anatomical Sciences, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Abstract
OBJECTIVE: The relationship between maternal age, duration of infertility, pre-ovulatory follicles, endometrial thickness and motile sperms with intra uterine insemination (IUI) success in women with infertility over 10 years was surveyed. METHODS: We performed a descriptive - cross sectional study among couples (n=26) with a history of infertility for more than 10 years who were treated with IUI. The data was collected between 2000 and 2007 in the fertility ward of Amiralmomenin Hospital of Semnan University of Medical Sciences. Patients underwent a basic fertility workup and the ovarian hyperstimulation was done with clomiphene citrate (CC) and human chorionic gonadotrophin (hMG) alone or in combination. A volume of 0.3-0.4 ml suspension of processed spermatozoa (after swim-up procedure) was introduced into the uterine cavity 36h after human chorionic gonadotrophin (hCG) administration. The comparison between variables was performed by chi-square and student's test on SPSS (Version 10.0). RESULTS: The total number of women with infertility over 10 years referring to fertility ward was 26. Seven of them became pregnant after treatment (27%). Majority of these pregnancies (87.5%) were achieved in the first cycle. Pregnant cases were 30-37 years of age with a history of infertility for up to ten years. The comparison of data between two groups showed that maternal age (P<0.03) and number of motile sperms (P<0.05) had a significant relationship with the results of treatment. CONCLUSION: Number of motile spermatozoa and women age are factors with the highest impact on pregnancy after IUI treatment in women with infertility for over 10 years.
OBJECTIVE: The relationship between maternal age, duration of infertility, pre-ovulatory follicles, endometrial thickness and motile sperms with intra uterine insemination (IUI) success in women with infertility over 10 years was surveyed. METHODS: We performed a descriptive - cross sectional study among couples (n=26) with a history of infertility for more than 10 years who were treated with IUI. The data was collected between 2000 and 2007 in the fertility ward of Amiralmomenin Hospital of Semnan University of Medical Sciences. Patients underwent a basic fertility workup and the ovarian hyperstimulation was done with clomiphene citrate (CC) and human chorionic gonadotrophin (hMG) alone or in combination. A volume of 0.3-0.4 ml suspension of processed spermatozoa (after swim-up procedure) was introduced into the uterine cavity 36h after human chorionic gonadotrophin (hCG) administration. The comparison between variables was performed by chi-square and student's test on SPSS (Version 10.0). RESULTS: The total number of women with infertility over 10 years referring to fertility ward was 26. Seven of them became pregnant after treatment (27%). Majority of these pregnancies (87.5%) were achieved in the first cycle. Pregnant cases were 30-37 years of age with a history of infertility for up to ten years. The comparison of data between two groups showed that maternal age (P<0.03) and number of motile sperms (P<0.05) had a significant relationship with the results of treatment. CONCLUSION: Number of motile spermatozoa and women age are factors with the highest impact on pregnancy after IUI treatment in women with infertility for over 10 years.
Authors: Fernanda Sicchieri; Aline Bomfim Silva; Ana Carolina Japur de Sá Rosa E Silva; Paula Andrea de Albuquerque Sales Navarro; Rui Alberto Ferriani; Rosana Maria Dos Reis Journal: JBRA Assist Reprod Date: 2018-03-01