BACKGROUND: The Organgruppe Mamma of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) performed a nationwide 3-phase analysis of the structure of care and standard of therapy given to patients with breast cancer from 2002 (4th quarter) to 2004 (4th quarter). The extent to which national and international treatment recommendations are implemented in routine clinical practice had so far not been evaluated in an interdisciplinary approach. No reliable data on the pattern of care of these patients have been published in Germany before. PATIENTS AND METHODS: The project included early breast cancer in the adjuvant and neoadjuvant setting as well as metastatic disease. We present the results of phase III of the AGO analysis, which are based on a survey conducted by the Organkommission Mamma in the 4th quarter of 2004. RESULTS: Evaluation of the data reveals that treatment based on the guidelines is now being implemented very reliably in certain sectors. This is of particular relevance to the pattern of adjuvant treatment in early breast cancer. In contrast, in metastatic breast cancer (MBC), the complexity of the interdisciplinary treatment approach is complicating this kind of straightforward analysis. CONCLUSION: The present analysis conducted by the AGO was the first attempt to analyse the treatment provided in patients presenting with MBC in a systematic fashion. The fundamental problem remains, irrespective of the stage of the tumour, that too few patients are treated in randomised clinical trials. The mission set by the AGO-Organkommission Mamma is the longitudinal observation of the therapy practices for breast cancer on the basis of the observations discussed here, which should ultimately benefit the optimisation of therapy quality in Germany.
BACKGROUND: The Organgruppe Mamma of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) performed a nationwide 3-phase analysis of the structure of care and standard of therapy given to patients with breast cancer from 2002 (4th quarter) to 2004 (4th quarter). The extent to which national and international treatment recommendations are implemented in routine clinical practice had so far not been evaluated in an interdisciplinary approach. No reliable data on the pattern of care of these patients have been published in Germany before. PATIENTS AND METHODS: The project included early breast cancer in the adjuvant and neoadjuvant setting as well as metastatic disease. We present the results of phase III of the AGO analysis, which are based on a survey conducted by the Organkommission Mamma in the 4th quarter of 2004. RESULTS: Evaluation of the data reveals that treatment based on the guidelines is now being implemented very reliably in certain sectors. This is of particular relevance to the pattern of adjuvant treatment in early breast cancer. In contrast, in metastatic breast cancer (MBC), the complexity of the interdisciplinary treatment approach is complicating this kind of straightforward analysis. CONCLUSION: The present analysis conducted by the AGO was the first attempt to analyse the treatment provided in patients presenting with MBC in a systematic fashion. The fundamental problem remains, irrespective of the stage of the tumour, that too few patients are treated in randomised clinical trials. The mission set by the AGO-Organkommission Mamma is the longitudinal observation of the therapy practices for breast cancer on the basis of the observations discussed here, which should ultimately benefit the optimisation of therapy quality in Germany.
Authors: G Von Minckwitz; K Brunnert; S D Costa; K Friedrichs; Ch Jackisch; B Gerber; N Harbeck; H Junkermann; V Möbus; U Nitz; G Schaller; A Scharl; Ch Thomssen; M Untch Journal: Zentralbl Gynakol Date: 2002-05
Authors: Matthias Schwenkglenks; Christian Jackisch; Manuel Constenla; Joseph N Kerger; Robert Paridaens; Leo Auerbach; André Bosly; Ruth Pettengell; Thomas D Szucs; Robert Leonard Journal: Support Care Cancer Date: 2006-04-19 Impact factor: 3.603
Authors: Hyman B Muss; Susan Woolf; Donald Berry; Constance Cirrincione; Raymond B Weiss; Daniel Budman; William C Wood; I Craig Henderson; Clifford Hudis; Eric Winer; Harvey Cohen; Judith Wheeler; Larry Norton Journal: JAMA Date: 2005-03-02 Impact factor: 56.272
Authors: Aron Goldhirsch; William C Wood; Richard D Gelber; Alan S Coates; Beat Thürlimann; Hans-Jörg Senn Journal: J Clin Oncol Date: 2003-07-07 Impact factor: 44.544
Authors: Steffen Dörfel; Claus-Christoph Steffens; Dirk Meyer; Hans Tesch; Lisa Kruggel; Melanie Frank; Martina Jänicke; Norbert Marschner Journal: Breast Cancer Date: 2017-12-04 Impact factor: 4.239
Authors: Jens Huober; Werner Fett; Arnd Nusch; Michael Neise; Marcus Schmidt; Arthur Wischnik; Steffen Gerhardt; Thomas Goehler; Hans-Joachim Lück; Andreas Rost Journal: BMC Cancer Date: 2010-01-05 Impact factor: 4.430