Literature DB >> 21371584

Fragment-based drug design - tools, practical approaches, and examples. Preface.

Lawrence C Kuo.   

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Year:  2011        PMID： 21371584     DOI： 10.1016/B978-0-12-381274-2.00029-7

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


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  10 in total

1.  Biosensor-based small molecule fragment screening with biolayer interferometry.

Authors:  Charles A Wartchow; Frank Podlaski; Shirley Li; Karen Rowan; Xiaolei Zhang; David Mark; Kuo-Sen Huang
Journal:  J Comput Aided Mol Des       Date:  2011-06-10       Impact factor: 3.686

2.  Protein-ligand structure guided by backbone and side-chain proton chemical shift perturbations.

Authors:  Clémentine Aguirre; Tim ten Brink; Olivier Cala; Jean-François Guichou; Isabelle Krimm
Journal:  J Biomol NMR       Date:  2014-09-26       Impact factor: 2.835

Review 3.  Biophysics in drug discovery: impact, challenges and opportunities.

Authors:  Jean-Paul Renaud; Chun-Wa Chung; U Helena Danielson; Ursula Egner; Michael Hennig; Roderick E Hubbard; Herbert Nar
Journal:  Nat Rev Drug Discov       Date:  2016-08-12       Impact factor: 84.694

4.  Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening.

Authors:  Joseph D Bauman; Disha Patel; Chhaya Dharia; Marc W Fromer; Sameer Ahmed; Yulia Frenkel; R S K Vijayan; J Thomas Eck; William C Ho; Kalyan Das; Aaron J Shatkin; Eddy Arnold
Journal:  J Med Chem       Date:  2013-02-20       Impact factor: 7.446

5.  Fragment screening of cyclin G-associated kinase by weak affinity chromatography.

Authors:  Elinor Meiby; Stefan Knapp; Jonathan M Elkins; Sten Ohlson
Journal:  Anal Bioanal Chem       Date:  2012-08-24       Impact factor: 4.142

6.  Low potency toxins reveal dense interaction networks in metabolism.

Authors:  William Bains
Journal:  BMC Syst Biol       Date:  2016-02-20

7.  An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.

Authors:  Tomer Meirson; Abraham O Samson; Hava Gil-Henn
Journal:  Drug Des Devel Ther       Date:  2017-05-18       Impact factor: 4.162

Review 8.  Assay design and development strategies for finding Hsp90 inhibitors and their role in human diseases.

Authors:  Monimoy Banerjee; Ishita Hatial; Bradley M Keegan; Brian S J Blagg
Journal:  Pharmacol Ther       Date:  2020-11-24       Impact factor: 12.310

9.  BcL-xL conformational changes upon fragment binding revealed by NMR.

Authors:  Clémentine Aguirre; Tim Ten Brink; Olivier Walker; Florence Guillière; Dany Davesne; Isabelle Krimm
Journal:  PLoS One       Date:  2013-05-23       Impact factor: 3.240

10.  Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.

Authors:  Agnieszka Krzyzosiak; Anna Sigurdardottir; Laura Luh; Marta Carrara; Indrajit Das; Kim Schneider; Anne Bertolotti
Journal:  Cell       Date:  2018-07-26       Impact factor: 41.582
  10 in total

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