Literature DB >> 21361198

Real-time dose computation: GPU-accelerated source modeling and superposition/convolution.

Robert Jacques1, John Wong, Russell Taylor, Todd McNutt.   

Abstract

PURPOSE: To accelerate dose calculation to interactive rates using highly parallel graphics processing units (GPUs).
METHODS: The authors have extended their prior work in GPU-accelerated superposition/ convolution with a modern dual-source model and have enhanced performance. The primary source algorithm supports both focused leaf ends and asymmetric rounded leaf ends. The extra-focal algorithm uses a discretized, isotropic area source and models multileaf collimator leaf height effects. The spectral and attenuation effects of static beam modifiers were integrated into each source's spectral function. The authors introduce the concepts of arc superposition and delta superposition. Arc superposition utilizes separate angular sampling for the total energy released per unit mass (TERMA) and superposition computations to increase accuracy and performance. Delta superposition allows single beamlet changes to be computed efficiently. The authors extended their concept of multi-resolution superposition to include kernel tilting. Multi-resolution superposition approximates solid angle ray-tracing, improving performance and scalability with a minor loss in accuracy. Superposition/convolution was implemented using the inverse cumulative-cumulative kernel and exact radiological path ray-tracing. The accuracy analyses were performed using multiple kernel ray samplings, both with and without kernel tilting and multi-resolution superposition.
RESULTS: Source model performance was <9 ms (data dependent) for a high resolution (4002) field using an NVIDIA (Santa Clara, CA) GeForce GTX 280. Computation of the physically correct multispectral TERMA attenuation was improved by a material centric approach, which increased performance by over 80%. Superposition performance was improved by approximately 24% to 0.058 and 0.94 s for 64(3) and 128(3) water phantoms; a speed-up of 101-144X over the highly optimized Pinnacle3 (Philips, Madison, WI) implementation. Pinnacle3 times were 8.3 and 94 s, respectively, on an AMD (Sunnyvale, CA) Opteron 254 (two cores, 2.8 GHz).
CONCLUSIONS: The authors have completed a comprehensive, GPU-accelerated dose engine in order to provide a substantial performance gain over CPU based implementations. Real-time dose computation is feasible with the accuracy levels of the superposition/convolution algorithm.

Entities:  

Mesh:

Year:  2011        PMID: 21361198     DOI: 10.1118/1.3483785

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  16 in total

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2.  Technical Note: scuda: A software platform for cumulative dose assessment.

Authors:  Seyoun Park; Todd McNutt; William Plishker; Harry Quon; John Wong; Raj Shekhar; Junghoon Lee
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Journal:  Radiat Oncol       Date:  2015-04-11       Impact factor: 3.481

5.  A kernel-based dose calculation algorithm for kV photon beams with explicit handling of energy and material dependencies.

Authors:  Anna Merle Reinhart; Martin F Fast; Peter Ziegenhein; Simeon Nill; Uwe Oelfke
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6.  Dosimetric validation and clinical implementation of two 3D dose verification systems for quality assurance in volumetric-modulated arc therapy techniques.

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7.  Validation of a GPU-Based 3D dose calculator for modulated beams.

Authors:  Saeed Ahmed; Dylan Hunt; Jeff Kapatoes; Robert Hayward; Geoffrey Zhang; Eduardo G Moros; Vladimir Feygelman
Journal:  J Appl Clin Med Phys       Date:  2017-03-29       Impact factor: 2.102

8.  A hybrid volumetric dose verification method for single-isocenter multiple-target cranial SRS.

Authors:  Saeed Ahmed; Jeff Kapatoes; Geoffrey Zhang; Eduardo G Moros; Vladimir Feygelman
Journal:  J Appl Clin Med Phys       Date:  2018-08-15       Impact factor: 2.102

9.  Improved outcome of 131I-mIBG treatment through combination with external beam radiotherapy in the SK-N-SH mouse model of neuroblastoma.

Authors:  Aurélien Corroyer-Dulmont; Nadia Falzone; Veerle Kersemans; James Thompson; Danny P Allen; Sarah Able; Christiana Kartsonaki; Javian Malcolm; Paul Kinchesh; Mark A Hill; Boris Vojnovic; Sean C Smart; Mark N Gaze; Katherine A Vallis
Journal:  Radiother Oncol       Date:  2017-06-05       Impact factor: 6.901

10.  An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.

Authors:  Veerle Kersemans; John S Beech; Stuart Gilchrist; Paul Kinchesh; Philip D Allen; James Thompson; Ana L Gomes; Zenobia D'Costa; Luke Bird; Iain D C Tullis; Robert G Newman; Aurelien Corroyer-Dulmont; Nadia Falzone; Abul Azad; Katherine A Vallis; Owen J Sansom; Ruth J Muschel; Borivoj Vojnovic; Mark A Hill; Emmanouil Fokas; Sean C Smart
Journal:  PLoS One       Date:  2017-04-28       Impact factor: 3.752

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