Literature DB >> 21361041

[Fingerprints of Tongmai Keli by HPLC-DAD-MS].

Bei-Jia Li1, Cheng Xiang, Xiu-Wei Yang, Li-Jun Wu, De-An Guo, Min Ye.   

Abstract

In order to clarify the chemical composition of Tongmai Keli, a HPLC fingerprint was established, and the 22 peaks were characterized by LC-DAD-MS. The herbal sources of these peaks were assigned. The results implied that genistin 8-C-glucoside, puerarin, daidzein 8-C-apiosyl (1, 6)-O-glucoside, daidzin, and salvianolic acid B were the main constituents of in Tongmai Keli. Ten batches of Tongmai Keli produced by different pharmaceutical companies were analyzed. Although different batches contained similar compounds, the contents of major compounds were significantly different. The method established in this study could be used for the quality control of Tongmai Keli.

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Year:  2010        PMID: 21361041

Source DB:  PubMed          Journal:  Yao Xue Xue Bao        ISSN: 0513-4870


  2 in total

1.  Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry.

Authors:  Fu-Rong Wang; Ying Zhang; Xin-Bao Yang; Chun-Xu Liu; Xiu-Wei Yang; Wei Xu; Jian-Xun Liu
Journal:  Molecules       Date:  2017-03-29       Impact factor: 4.411

2.  Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer.

Authors:  Shuai Wu; Wei Xu; Fu-Rong Wang; Xiu-Wei Yang
Journal:  Molecules       Date:  2015-10-15       Impact factor: 4.411

  2 in total

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