Literature DB >> 21358723

Learning lessons from Pfizer's $800 million failure.

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Year:  2011        PMID: 21358723     DOI: 10.1038/nrd3401

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  3 in total

1.  Safety of anacetrapib in patients with or at high risk for coronary heart disease.

Authors:  Christopher P Cannon; Sukrut Shah; Hayes M Dansky; Michael Davidson; Eliot A Brinton; Antonio M Gotto; Michael Stepanavage; Sherry Xueyu Liu; Patrice Gibbons; Tanya B Ashraf; Jennifer Zafarino; Yale Mitchel; Philip Barter
Journal:  N Engl J Med       Date:  2010-11-17       Impact factor: 91.245

2.  Effects of torcetrapib in patients at high risk for coronary events.

Authors:  Philip J Barter; Mark Caulfield; Mats Eriksson; Scott M Grundy; John J P Kastelein; Michel Komajda; Jose Lopez-Sendon; Lori Mosca; Jean-Claude Tardif; David D Waters; Charles L Shear; James H Revkin; Kevin A Buhr; Marian R Fisher; Alan R Tall; Bryan Brewer
Journal:  N Engl J Med       Date:  2007-11-05       Impact factor: 91.245

3.  Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone.

Authors:  M J Forrest; D Bloomfield; R J Briscoe; P N Brown; A-M Cumiskey; J Ehrhart; J C Hershey; W J Keller; X Ma; H E McPherson; E Messina; L B Peterson; W Sharif-Rodriguez; P K S Siegl; P J Sinclair; C P Sparrow; A S Stevenson; S-Y Sun; C Tsai; H Vargas; M Walker; S H West; V White; R F Woltmann
Journal:  Br J Pharmacol       Date:  2008-06-09       Impact factor: 8.739

  3 in total
  6 in total

1.  Medicinal chemistry for 2020.

Authors:  Seetharama D Satyanarayanajois; Ronald A Hill
Journal:  Future Med Chem       Date:  2011-10       Impact factor: 3.808

2.  Why Drugs Fail in Late Stages of Development: Case Study Analyses from the Last Decade and Recommendations.

Authors:  Dolly A Parasrampuria; Leslie Z Benet; Amarnath Sharma
Journal:  AAPS J       Date:  2018-03-13       Impact factor: 4.009

3.  Compound signature detection on LINCS L1000 big data.

Authors:  Chenglin Liu; Jing Su; Fei Yang; Kun Wei; Jinwen Ma; Xiaobo Zhou
Journal:  Mol Biosyst       Date:  2015-01-22

Review 4.  Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib.

Authors:  Alyse S Goldberg; Robert A Hegele
Journal:  Drug Des Devel Ther       Date:  2012-09-24       Impact factor: 4.162

Review 5.  Three-dimensional bio-printing: A new frontier in oncology research.

Authors:  Nitin Charbe; Paul A McCarron; Murtaza M Tambuwala
Journal:  World J Clin Oncol       Date:  2017-02-10

6.  The repeated setbacks of HIV vaccine development laid the groundwork for SARS-CoV-2 vaccines.

Authors:  Jeffrey E Harris
Journal:  Health Policy Technol       Date:  2022-03-21       Impact factor: 5.211

  6 in total

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