Giovanni A Fava1, Eliana Tossani. 1. Department of Psychology, University of Bologna, Bologna, Italy. giovanniandrea.fava@unibo.it
Abstract
AIM: The aim of this review was to survey the available literature on prodromal symptoms of unipolar major depression. METHODS: Both a computerized (Medline) and a manual search of the literature were performed. RESULTS: In a substantial proportion of patients with depression a prodromal phase can be identified. There is a relationship between residual and prodromal symptomatology (the rollback phenomenon). CONCLUSIONS: Appraisal of prodromal phase of major depression has important implications as to pathophysiological models of disease and relapse prevention. It may allow a staging system of depressive illness that may yield more enduring results in the therapeutic efforts.
AIM: The aim of this review was to survey the available literature on prodromal symptoms of unipolar major depression. METHODS: Both a computerized (Medline) and a manual search of the literature were performed. RESULTS: In a substantial proportion of patients with depression a prodromal phase can be identified. There is a relationship between residual and prodromal symptomatology (the rollback phenomenon). CONCLUSIONS: Appraisal of prodromal phase of major depression has important implications as to pathophysiological models of disease and relapse prevention. It may allow a staging system of depressive illness that may yield more enduring results in the therapeutic efforts.
Authors: Michael W Otto; Jeffrey L Birk; Hayley E Fitzgerald; Gregory V Chauvin; Alexandra K Gold; Jenna R Carl Journal: Clin Psychol Rev Date: 2022-05-23
Authors: Mieke Klein Hofmeijer-Sevink; Neeltje M Batelaan; Harold J G M van Megen; Marcel A van den Hout; Brenda W Penninx; Anton J L M van Balkom; Danielle C Cath Journal: Can J Psychiatry Date: 2017-05-16 Impact factor: 4.356