Literature DB >> 21350495

New insights into oncogenic stress.

Kevin M Haigis, Alejandro Sweet-Cordero.   

Abstract

Expression of oncogenes in otherwise normal cells often leads to the activation of anti-oncogenic pathways through a poorly understood process described as 'oncogenic stress'. A new study implicates the Jnk pathway signaling in the activation of p53 in response to both K-Ras and Neu oncogene expression.

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Year:  2011        PMID： 21350495     DOI： 10.1038/ng0311-177

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

1.  Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.

Authors:  M Serrano; A W Lin; M E McCurrach; D Beach; S W Lowe
Journal:  Cell       Date:  1997-03-07       Impact factor: 41.582

2.  MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines.

Authors:  C Tournier; C Dong; T K Turner; S N Jones; R A Flavell; R J Davis
Journal:  Genes Dev       Date:  2001-06-01       Impact factor: 11.361

3.  The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression.

Authors:  Daniel Schramek; Athanassios Kotsinas; Arabella Meixner; Teiji Wada; Ulrich Elling; J Andrew Pospisilik; G Gregory Neely; Ralf-Harun Zwick; Verena Sigl; Guido Forni; Manuel Serrano; Vassilis G Gorgoulis; Josef M Penninger
Journal:  Nat Genet       Date:  2011-02-13       Impact factor: 38.330

4.  DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.

Authors:  Jirina Bartkova; Zuzana Horejsí; Karen Koed; Alwin Krämer; Frederic Tort; Karsten Zieger; Per Guldberg; Maxwell Sehested; Jahn M Nesland; Claudia Lukas; Torben Ørntoft; Jiri Lukas; Jiri Bartek
Journal:  Nature       Date:  2005-04-14       Impact factor: 49.962

Review 5.  p53: guardian of the genome and policeman of the oncogenes.

Authors:  Alejo Efeyan; Manuel Serrano
Journal:  Cell Cycle       Date:  2007-05-28       Impact factor: 4.534

6.  Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

Authors:  David MacPherson; Jungho Kim; Teresa Kim; Byung Kirl Rhee; Conny Th M Van Oostrom; Richard A DiTullio; Monica Venere; Thanos D Halazonetis; Roderick Bronson; Annemieke De Vries; Mark Fleming; Tyler Jacks
Journal:  EMBO J       Date:  2004-09-02       Impact factor: 11.598

Review 7.  Tumour suppression by p53: a role for the DNA damage response?

Authors:  David W Meek
Journal:  Nat Rev Cancer       Date:  2009-09-04       Impact factor: 60.716

8.  Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

Authors:  Thomas Kuilman; Chrysiis Michaloglou; Liesbeth C W Vredeveld; Sirith Douma; Remco van Doorn; Christophe J Desmet; Lucien A Aarden; Wolter J Mooi; Daniel S Peeper
Journal:  Cell       Date:  2008-06-13       Impact factor: 41.582

9.  Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Authors:  Jean-Philippe Coppé; Christopher K Patil; Francis Rodier; Yu Sun; Denise P Muñoz; Joshua Goldstein; Peter S Nelson; Pierre-Yves Desprez; Judith Campisi
Journal:  PLoS Biol       Date:  2008-12-02       Impact factor: 8.029

10.  Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.

Authors:  David Dankort; David P Curley; Robert A Cartlidge; Betsy Nelson; Anthony N Karnezis; William E Damsky; Mingjian J You; Ronald A DePinho; Martin McMahon; Marcus Bosenberg
Journal:  Nat Genet       Date:  2009-03-12       Impact factor: 38.330
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  20 in total

1.  Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality.

Authors:  Sunitha Rangaraju; Gregory M Solis; Ryan C Thompson; Rafael L Gomez-Amaro; Leo Kurian; Sandra E Encalada; Alexander B Niculescu; Daniel R Salomon; Michael Petrascheck
Journal:  Elife       Date:  2015-12-01       Impact factor: 8.140

2.  MKK7 and ARF: new players in the DNA damage response scenery.

Authors:  Athanassios Kotsinas; Panagiota Papanagnou; Panagiotis Galanos; Daniel Schramek; Paul Townsend; Josef M Penninger; Jiri Bartek; Vassilis G Gorgoulis
Journal:  Cell Cycle       Date:  2014-03-26       Impact factor: 4.534

3.  Anoikis of colon carcinoma cells triggered by β-catenin loss can be enhanced by tumor necrosis factor receptor 1 antagonists.

Authors:  B H Yoo; O Masson; Y Li; I A Khan; P S Gowda; K V Rosen
Journal:  Oncogene       Date:  2014-12-22       Impact factor: 9.867

4.  Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells.

Authors:  Byong Hoon Yoo; Iman Aftab Khan; Ananda Koomson; Pramod Gowda; Takehiko Sasazuki; Senji Shirasawa; Shashi Gujar; Kirill V. Rosen
Journal:  Autophagy       Date:  2017-12-21       Impact factor: 16.016

5.  Mutant BRAF induces DNA strand breaks, activates DNA damage response pathway, and up-regulates glucose transporter-1 in nontransformed epithelial cells.

Authors:  Jim Jinn-Chyuan Sheu; Bin Guan; Fuu-Jen Tsai; Erin Yi-Ting Hsiao; Chih-Mei Chen; Raquel Seruca; Tian-Li Wang; Ie-Ming Shih
Journal:  Am J Pathol       Date:  2012-01-05       Impact factor: 4.307

6.  TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma--evidence supporting the clonal relationship of the two lesions.

Authors:  Elisabetta Kuhn; Robert J Kurman; Russell Vang; Ann Smith Sehdev; Guangming Han; Robert Soslow; Tian-Li Wang; Ie-Ming Shih
Journal:  J Pathol       Date:  2011-12-23       Impact factor: 7.996

Review 7.  Effects of aneuploidy on cell behaviour and function.

Authors:  Rong Li; Jin Zhu
Journal:  Nat Rev Mol Cell Biol       Date:  2022-01-05       Impact factor: 113.915

8.  Malate dehydrogenase 2 confers docetaxel resistance via regulations of JNK signaling and oxidative metabolism.

Authors:  Qiong Liu; Chris T Harvey; Hao Geng; Changhui Xue; Vivian Chen; Tomasz M Beer; David Z Qian
Journal:  Prostate       Date:  2013-02-06       Impact factor: 4.104

Review 9.  Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.

Authors:  Tamara Tchkonia; Yi Zhu; Jan van Deursen; Judith Campisi; James L Kirkland
Journal:  J Clin Invest       Date:  2013-03-01       Impact factor: 14.808

10.  Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

Authors:  David Lindgren; Gottfrid Sjödahl; Martin Lauss; Johan Staaf; Gunilla Chebil; Kristina Lövgren; Sigurdur Gudjonsson; Fredrik Liedberg; Oliver Patschan; Wiking Månsson; Mårten Fernö; Mattias Höglund
Journal:  PLoS One       Date:  2012-06-07       Impact factor: 3.240
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