Literature DB >> 21346569

The current status of postconcussion syndrome.

George P Prigatano1, Shawn D Gale.   

Abstract

PURPOSE OF REVIEW: Concussion produces a brief disruption in mental status and is associated with a variety of physical and cognitive symptoms which typically diminish during the first several days to weeks posttrauma. This review highlights problems in defining and measuring concussion, the mildest form of traumatic brain injury (TBI). Furthermore, the 'natural' course of recovery correlates of postconcussion syndrome (PCS) and guidelines for clinical management are discussed. RECENT
FINDINGS: Traditional measures of TBI severity (e.g. length of loss of consciousness or period of posttraumatic amnesia) do not correlate with persistent concussion symptoms. Abnormal eye movements, cerebrovascular disturbances, extra-axial injuries, alcohol intoxication at time of injury, and presence of an axis I disorder are associated with persistent symptoms. Early management of physical, cognitive, and emotional symptoms following concussion may reduce long-term morbidity. Techniques used to help concussed athletes return to play appear useful when evaluating and treating concussion in nonathletes.
SUMMARY: The study of concussion and PCS has increased significantly over the past 10 years, with recent research supporting an underlying biological cause for initial symptomatology. Persistent symptoms may be associated with both neurological and non-neurological variables. Early and serial monitoring and treatment of symptoms appears to result in substantial improvement in the vast majority of concussed patients.

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Year:  2011        PMID: 21346569     DOI: 10.1097/YCO.0b013e328344698b

Source DB:  PubMed          Journal:  Curr Opin Psychiatry        ISSN: 0951-7367            Impact factor:   4.741


  10 in total

Review 1.  Neuroimaging biomarkers in mild traumatic brain injury (mTBI).

Authors:  Erin D Bigler
Journal:  Neuropsychol Rev       Date:  2013-08-24       Impact factor: 7.444

2.  A study on the mechanism by which MDMA protects against dopaminergic dysfunction after minimal traumatic brain injury (mTBI) in mice.

Authors:  S Edut; V Rubovitch; M Rehavi; S Schreiber; C G Pick
Journal:  J Mol Neurosci       Date:  2014-08-16       Impact factor: 3.444

3.  MR Imaging Applications in Mild Traumatic Brain Injury: An Imaging Update.

Authors:  Xin Wu; Ivan I Kirov; Oded Gonen; Yulin Ge; Robert I Grossman; Yvonne W Lui
Journal:  Radiology       Date:  2016-06       Impact factor: 11.105

4.  Concurrent vision dysfunctions in convergence insufficiency with traumatic brain injury.

Authors:  Tara L Alvarez; Eun H Kim; Vincent R Vicci; Sunil K Dhar; Bharat B Biswal; A M Barrett
Journal:  Optom Vis Sci       Date:  2012-12       Impact factor: 1.973

Review 5.  Exercise for Sport-Related Concussion and Persistent Postconcussive Symptoms.

Authors:  Mohammad Nadir Haider; Itai Bezherano; Alex Wertheimer; Akas H Siddiqui; Emily C Horn; Barry S Willer; John J Leddy
Journal:  Sports Health       Date:  2020-11-04       Impact factor: 3.843

Review 6.  Repetitive concussions in adolescent athletes - translating clinical and experimental research into perspectives on rehabilitation strategies.

Authors:  Bridgette D Semple; Sangmi Lee; Raha Sadjadi; Nora Fritz; Jaclyn Carlson; Carrie Griep; Vanessa Ho; Patrice Jang; Annick Lamb; Beth Popolizio; Sonia Saini; Jeffrey J Bazarian; Mayumi L Prins; Donna M Ferriero; D Michele Basso; Linda J Noble-Haeusslein
Journal:  Front Neurol       Date:  2015-04-02       Impact factor: 4.003

7.  Bicycling-related concussions leading to postconcussion syndrome in adults.

Authors:  Connor Moore; Paria Baharikhoob; Mozhgan Khodadadi; Charles H Tator
Journal:  BMJ Open Sport Exerc Med       Date:  2020-03-30

8.  Transcranial Direct Current Stimulation for Post-Concussion Syndrome: Study Protocol for a Randomized Crossover Trial.

Authors:  Robson Luis Oliveira de Amorim; André Russowsky Brunoni; Mirian Akiko Furutani de Oliveira; Ana Luiza Costa Zaninotto; Marcia Mitie Nagumo; Vinícius Monteiro de Paula Guirado; Iuri Santana Neville; Gláucia Rosana Guerra Benute; Mara Cristina Souza de Lucia; Wellingson Silva Paiva; Almir Ferreira de Andrade; Manoel Jacobsen Teixeira
Journal:  Front Neurol       Date:  2017-05-02       Impact factor: 4.003

9.  DTI measures identify mild and moderate TBI cases among patients with complex health problems: A receiver operating characteristic analysis of U.S. veterans.

Authors:  Keith L Main; Salil Soman; Franco Pestilli; Ansgar Furst; Art Noda; Beatriz Hernandez; Jennifer Kong; Jauhtai Cheng; Jennifer K Fairchild; Joy Taylor; Jerome Yesavage; J Wesson Ashford; Helena Kraemer; Maheen M Adamson
Journal:  Neuroimage Clin       Date:  2017-06-24       Impact factor: 4.881

10.  Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure.

Authors:  Dara L Dickstein; Rita De Gasperi; Miguel A Gama Sosa; Georgina Perez-Garcia; Jennifer A Short; Heidi Sosa; Gissel M Perez; Anna E Tschiffely; Kristen Dams-O'Connor; Mariel Y Pullman; Karin Knesaurek; Andrew Knutsen; Dzung L Pham; Lale Soleimani; Barry D Jordan; Wayne A Gordon; Bradley N Delman; Gleb Shumyatsky; Pashtun-Poh Shahim; Steven T DeKosky; James R Stone; Elaine Peskind; Kaj Blennow; Henrik Zetterberg; Steven A Chance; Mario Torso; Lale Kostakoglu; Mary Sano; Patrick R Hof; Stephen T Ahlers; Sam Gandy; Gregory A Elder
Journal:  Mol Psychiatry       Date:  2020-02-25       Impact factor: 15.992

  10 in total

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